Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50029852
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288674(CHEMBL420674 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288672(CHEMBL113362 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288673(CHEMBL264455 | {4-[((S)-1-Benzoyl-pyrrolidine-2-ca...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288683(CHEMBL109438 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288672(CHEMBL113362 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288677(CHEMBL324691 | [(E)-4-(1,3-Dioxo-1,3-dihydro-isoin...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288677(CHEMBL324691 | [(E)-4-(1,3-Dioxo-1,3-dihydro-isoin...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288678(CHEMBL320968 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288681((4-Benzoylamino-butyl)-[(S)-2-((S)-3-methyl-1-phen...)
Affinity DataKi:  5.70nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288687(CHEMBL111975 | {4-[((S)-1-Acetyl-pyrrolidine-2-car...)
Affinity DataKi:  6.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288678(CHEMBL320968 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288683(CHEMBL109438 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  12nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288673(CHEMBL264455 | {4-[((S)-1-Benzoyl-pyrrolidine-2-ca...)
Affinity DataKi:  13nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288699((4-Ethoxycarbonylamino-butyl)-[(S)-2-((S)-3-methyl...)
Affinity DataKi:  16nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288668(CHEMBL109829 | [4-(3-Ethyl-ureido)-butyl]-[(S)-2-(...)
Affinity DataKi:  17nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288668(CHEMBL109829 | [4-(3-Ethyl-ureido)-butyl]-[(S)-2-(...)
Affinity DataKi:  19nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288674(CHEMBL420674 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  20nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288682(CHEMBL110991 | {4-[((R)-1-Benzoyl-pyrrolidine-2-ca...)
Affinity DataKi:  24nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288675(CHEMBL113234 | {4-[((R)-1-Acetyl-pyrrolidine-2-car...)
Affinity DataKi:  26nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288681((4-Benzoylamino-butyl)-[(S)-2-((S)-3-methyl-1-phen...)
Affinity DataKi:  26nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288679(CHEMBL325835 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  30nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288684(CHEMBL324004 | [4-(3-Benzyl-ureido)-butyl]-[(S)-2-...)
Affinity DataKi:  50nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288693((4-Methoxycarbonylamino-butyl)-[(S)-2-((S)-3-methy...)
Affinity DataKi:  54nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288694(CHEMBL322142 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  56nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288687(CHEMBL111975 | {4-[((S)-1-Acetyl-pyrrolidine-2-car...)
Affinity DataKi:  62nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288695((4-Benzyloxycarbonylamino-butyl)-[(S)-2-((S)-3-met...)
Affinity DataKi:  63nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288685(CHEMBL110253 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  70nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288690(CHEMBL109670 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  130nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288679(CHEMBL325835 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  130nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288669(CHEMBL109671 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  170nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288698(CHEMBL112724 | {[2-(1,3-Dioxo-1,3-dihydro-isoindol...)
Affinity DataKi:  410nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288691(CHEMBL111601 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  440nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288696(CHEMBL110075 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  470nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288676(3-{Hydroxy-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-...)
Affinity DataKi:  520nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288697((2-Benzylcarbamoyl-ethyl)-[(S)-2-((S)-3-methyl-1-p...)
Affinity DataKi:  540nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288680(CHEMBL326018 | Methyl-[(S)-2-((S)-3-methyl-1-pheny...)
Affinity DataKi:  570nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288671(CHEMBL110997 | [(S)-2-((S)-3-Methyl-1-phenylcarbam...)
Affinity DataKi:  670nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288676(3-{Hydroxy-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288680(CHEMBL326018 | Methyl-[(S)-2-((S)-3-methyl-1-pheny...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288670((4-Amino-butyl)-[(S)-2-((S)-3-methyl-1-phenylcarba...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288691(CHEMBL111601 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288686(CHEMBL110312 | Phosphinic acid derivative)
Affinity DataIC50:  50nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288686(CHEMBL110312 | Phosphinic acid derivative)
Affinity DataIC50:  260nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288692(CHEMBL324006 | [(S)-2-((S)-1-Benzylcarbamoyl-3-met...)
Affinity DataIC50:  430nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288688(CHEMBL419395 | Phosphinic acid derivative)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288692(CHEMBL324006 | [(S)-2-((S)-1-Benzylcarbamoyl-3-met...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288688(CHEMBL419395 | Phosphinic acid derivative)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288689(CHEMBL113500 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288689(CHEMBL113500 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article