Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50029883
TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 20nMAssay Description:Compound was evaluated for inhibitory activity against Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1s subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 140nMAssay Description:Compound was evaluated for inhibitory activity against C1s serine protease. More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 240nMAssay Description:Compound was evaluated for inhibitory activity against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 290nMAssay Description:Compound was evaluated for inhibitory activity against Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 510nMAssay Description:Compound was evaluated for inhibitory activity against Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKallikrein-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 650nMAssay Description:Compound was evaluated for inhibitory activity against Kallikrein.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289007BDBM50289007(2-(2-Iodo-phenyl)-naphtho[2,3-d][1,3]oxazin-4-one ...)
Affinity DataIC50: 700nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.04E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease. More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1s subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 1.25E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1s serine protease. More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 1.37E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease. More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease in assay 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50288998BDBM50288998(6,7-Dichloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289016BDBM50289016(5-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289004BDBM50289004(6-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50288996BDBM50288996(2-(2-Trifluoromethyl-phenyl)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289011BDBM50289011(2-(2-Iodo-phenyl)-6-methoxy-benzo[d][1,3]oxazin-4-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289009BDBM50289009(2-(2-Iodo-benzyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 6.68E+3nMAssay Description:Compound was evaluated for inhibitory activity against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50288997BDBM50288997(2-(2-Iodo-phenyl)-5-methyl-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289004BDBM50289004(6-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289006BDBM50289006(2-(2-Bromo-phenyl)-benzo[d][1,3]oxazin-4-one | CHE...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKallikrein-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 9.89E+3nMAssay Description:Compound was evaluated for inhibitory activity against Kallikrein.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289008BDBM50289008(2-(2-Iodo-phenyl)-6-methyl-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063698BDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289012BDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | CH...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289016BDBM50289016(5-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 33703BDBM33703(MLS000551096 | cid_347675 | SMR000174492 | 2-(2-Ni...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 1.53E+4nMAssay Description:Compound was evaluated for inhibitory activity against Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289010BDBM50289010(2-(2-Chloro-phenyl)-benzo[d][1,3]oxazin-4-one | CH...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289000BDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | C...)
Affinity DataIC50: 1.77E+4nMAssay Description:Compound was evaluated for percentage inhibitory activity against C1r serine protease in assay 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289017BDBM50289017(2-(2-Iodo-phenyl)-7-nitro-benzo[d][1,3]oxazin-4-on...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289009BDBM50289009(2-(2-Iodo-benzyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289004BDBM50289004(6-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289006BDBM50289006(2-(2-Bromo-phenyl)-benzo[d][1,3]oxazin-4-one | CHE...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50288996BDBM50288996(2-(2-Trifluoromethyl-phenyl)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 33703BDBM33703(MLS000551096 | cid_347675 | SMR000174492 | 2-(2-Ni...)
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289009BDBM50289009(2-(2-Iodo-benzyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289010BDBM50289010(2-(2-Chloro-phenyl)-benzo[d][1,3]oxazin-4-one | CH...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289006BDBM50289006(2-(2-Bromo-phenyl)-benzo[d][1,3]oxazin-4-one | CHE...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063703BDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease in assay 2 at t=60 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289008BDBM50289008(2-(2-Iodo-phenyl)-6-methyl-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289016BDBM50289016(5-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289007BDBM50289007(2-(2-Iodo-phenyl)-naphtho[2,3-d][1,3]oxazin-4-one ...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289013BDBM50289013(2-(3-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289012BDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | CH...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289002BDBM50289002(7-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetComplement C1r subcomponent(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289001BDBM50289001(2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazi...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

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