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Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50029943
TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  0.467nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  0.505nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  6.20nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  141nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  396nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  447nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  791nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  905nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetTissue-type plasminogen activator(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetTissue-type plasminogen activator(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetTissue-type plasminogen activator(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetTissue-type plasminogen activator(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetTissue-type plasminogen activator(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article