Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50029950
LigandChemical structure of BindingDB Monomer ID 50289610BDBM50289610([3-(4,5,7-Trifluoro-benzothiazol-2-ylmethyl)-pheny...)
Affinity DataIC50: 6.60nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289614BDBM50289614([3-Chloro-5-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289613BDBM50289613({Phenyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-pro...)
Affinity DataIC50: 8.30nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289624BDBM50289624({Phenyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-thi...)
Affinity DataIC50: 8.40nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289628BDBM50289628(3-Carboxymethyl-5-(4,5,7-trifluoro-benzothiazol-2-...)
Affinity DataIC50: 8.70nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289617BDBM50289617([3-Fluoro-5-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 8.80nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289616BDBM50289616([2-Chloro-3-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 9.30nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289621BDBM50289621([3-Bromo-5-(4,5,7-trifluoro-benzothiazol-2-ylmethy...)
Affinity DataIC50: 9.40nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289629BDBM50289629([3-Oxo-4-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)...)
Affinity DataIC50: 9.5nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289612BDBM50289612([3-Methyl-5-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 9.60nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289625BDBM50289625({Benzyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-pro...)
Affinity DataIC50: 9.70nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289615BDBM50289615([3-Iodo-5-(4,5,7-trifluoro-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289620BDBM50289620({Methyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-thi...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 16496BDBM16496(CHEMBL10413 | FR 74366 | [3-(4-bromo-2-fluorobenzy...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50289619BDBM50289619([3-Dimethylamino-5-(4,5,7-trifluoro-benzothiazol-2...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289623BDBM50289623({Methyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-pro...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 16314BDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50289626BDBM50289626([2-(4,5,7-Trifluoro-benzothiazol-2-ylmethyl)-pheny...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289611BDBM50289611({Phenethyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289622BDBM50289622({Benzyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-thi...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289618BDBM50289618([4-(4,5,7-Trifluoro-benzothiazol-2-ylmethyl)-pheny...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50289627BDBM50289627(6-(4,5,7-Trifluoro-benzothiazol-2-yl)-hexanoic aci...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article