Compile Data Set for Download or QSAR
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Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50030083
TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287391((R)-4-Methyl-2-[2-oxo-2-(9H-xanthen-9-yl)-ethyl]-p...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290965((R)-4-Methyl-2-[2-(naphthalene-2-sulfinyl)-ethyl]-...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290966((R)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290965((R)-4-Methyl-2-[2-(naphthalene-2-sulfinyl)-ethyl]-...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290963((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290963((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290966((R)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290964((S)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In DepthDetails Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290964((S)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In DepthDetails Article