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Found 15 Enz. Inhib. hit(s) with all data for entry = 50030088
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  1.10nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  1.40nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  2.60nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  5nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  6.20nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50:  12nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  15nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50:  16nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  30nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  290nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  315nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  791nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50:  923nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In DepthDetails Article