Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50034748
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: <1nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281638((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imi...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to reninMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281636((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to reninMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin E(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281636((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  3nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin EMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281641((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  4nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281638((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imi...)
Affinity DataKi:  5nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281642(((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-...)
Affinity DataKi:  8nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281640(CHEMBL433729 | Pyridine-2-carboxylic acid ((1S,2S,...)
Affinity DataKi:  8nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281651((2S,4S,5S)-5-Acetylamino-6-cyclohexyl-4-hydroxy-2-...)
Affinity DataKi:  8nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281636((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  9nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281648(CHEMBL166640 | [(S)-1-((1S,2S,4S)-1-Cyclohexylmeth...)
Affinity DataKi:  10nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50281636((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  12nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to pepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281644(CHEMBL355867 | N*1*-[(1S,2S,4S)-1-Cyclohexylmethyl...)
Affinity DataKi:  14nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281643((2S,4S,5S)-5-Acetylamino-6-cyclohexyl-4-hydroxy-2-...)
Affinity DataKi:  16nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281652((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-2-isopropyl-5-{(...)
Affinity DataKi:  30nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  30nMAssay Description:Tested for the inhibition of HIV-2 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281639((2S,4S,5S)-6-Cyclohexyl-5-hexanoylamino-4-hydroxy-...)
Affinity DataKi:  47nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin E(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281638((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imi...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin EMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281637((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-2-isopropyl-5-{(...)
Affinity DataKi:  61nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281646((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-2-isopropyl-5-(2...)
Affinity DataKi:  61nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50281636((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  65nMAssay Description:Compound was evaluated for the inhibition of HIV-2 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281645((2S,4S,5S)-6-Cyclohexyl-5-(3,3-dimethyl-butyrylami...)
Affinity DataKi:  75nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin E(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281642(((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-...)
Affinity DataKi:  90nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin EMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281642(((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-...)
Affinity DataKi:  100nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin E(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  142nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin EMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50281638((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imi...)
Affinity DataKi:  170nMAssay Description:Compound was evaluated for the inhibition of HIV-2 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281638((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imi...)
Affinity DataKi:  200nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281636((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  212nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to reninMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  265nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to pepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50281638((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imi...)
Affinity DataKi:  290nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to pepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50281642(((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-...)
Affinity DataKi:  330nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to pepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281650((2S,4S,5S)-5-Amino-6-cyclohexyl-4-hydroxy-2-isopro...)
Affinity DataKi:  800nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281649((S)-2-((2S,4S,5S)-5-{(S)-3-Carbamoyl-2-[(quinoline...)
Affinity DataKi: >1.00E+3nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281647((2S,4S,5S)-5-Acetylamino-6-cyclohexyl-4-hydroxy-2-...)
Affinity DataKi: >1.00E+3nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281642(((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to reninMore data for this Ligand-Target Pair
In DepthDetails Article