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Found 20 Enz. Inhib. hit(s) with all data for entry = 50034766
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  4.20nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282586(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(phosphonome...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282588(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-phenyl-1-...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282589(2-{(S)-2-[3-(4-Hydroxy-phenyl)-1-phosphono-propyla...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282593(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-naphthale...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282593(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-naphthale...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282592(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(1-phosphono...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282587(3-(S)-1H-Indol-3-yl-2-{(S)-2-[3-(1H-indol-3-yl)-1-...)
Affinity DataIC50:  560nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282595(CHEMBL281562 | PO3 2-Leu-Trp-O-3K)
Affinity DataIC50:  960nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282588(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-phenyl-1-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282590(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(4-phenyl-1-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282585(CHEMBL22509 | PO3 2-Nle-Trp-O-3K)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282587(3-(S)-1H-Indol-3-yl-2-{(S)-2-[3-(1H-indol-3-yl)-1-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282591(CHEMBL281785 | PO3 2-Ile-Trp-O-3K)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282589(2-{(S)-2-[3-(4-Hydroxy-phenyl)-1-phosphono-propyla...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282586(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(phosphonome...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282590(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(4-phenyl-1-...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282594(CHEMBL280917 | PO3 2-Leu-Nal-O-3K)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282592(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(1-phosphono...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article