Compile Data Set for Download or QSAR
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Found 22 Enz. Inhib. hit(s) with all data for entry = 50034800
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)
Affinity DataIC50:  0.210nMAssay Description:Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50050641(CHEMBL45340 | PD-161182 | [(R)-2-(2,3-Difluoro-phe...)
Affinity DataIC50:  3.70nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 3 binding sites in guinea pig cortical membranes using [125I][MePhe7]-NKB as rad...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050641(CHEMBL45340 | PD-161182 | [(R)-2-(2,3-Difluoro-phe...)
Affinity DataIC50:  3.70nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 3 binding sites in guinea pig cortical membranes using [125I][MePhe7]-NKB as rad...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataIC50:  10nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50050652(CHEMBL47146 | PD-160946 | [(R)-2-(2-Fluoro-phenyl)...)
Affinity DataIC50:  14nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 3 binding sites in guinea pig cortical membranes using [125I]-[MePhe7]-Neurokini...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050652(CHEMBL47146 | PD-160946 | [(R)-2-(2-Fluoro-phenyl)...)
Affinity DataIC50:  16nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050649(CHEMBL444832 | {(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-...)
Affinity DataIC50:  16nMAssay Description:Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50052524((S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-m...)
Affinity DataIC50:  21nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050649(CHEMBL444832 | {(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-...)
Affinity DataIC50:  40nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050642(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
Affinity DataIC50:  40nMAssay Description:Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050674(CHEMBL44965 | [(R)-1-Methyl-2-phenyl-1-(7-ureido-h...)
Affinity DataIC50:  43nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050680(CHEMBL47641 | [(R)-1-(8-Hydroxy-octylcarbamoyl)-1-...)
Affinity DataIC50:  52nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050654(CHEMBL44686 | [(R)-1-Methyl-2-phenyl-1-((S)-1-phen...)
Affinity DataIC50:  74nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050643(CHEMBL296983 | [(R)-1-(8-Hydroxy-octylcarbamoyl)-1...)
Affinity DataIC50:  350nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(HAMSTER)
TBA

Curated by ChEMBL
LigandPNGBDBM50050641(CHEMBL45340 | PD-161182 | [(R)-2-(2,3-Difluoro-phe...)
Affinity DataIC50:  790nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 2 binding sites in membranes prepared from hamster urinary bladder using [125I]n...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284945(CHEMBL48731 | [(R)-2-(1H-Indol-2-yl)-1-methyl-1-(1...)
Affinity DataIC50:  1.20E+3nMAssay Description:Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284945(CHEMBL48731 | [(R)-2-(1H-Indol-2-yl)-1-methyl-1-(1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was tested for binding affinity against human NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(HAMSTER)
TBA

Curated by ChEMBL
LigandPNGBDBM50050652(CHEMBL47146 | PD-160946 | [(R)-2-(2-Fluoro-phenyl)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 2 binding sites in membranes prepared from hamster urinary bladder using [125I]n...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050675(CHEMBL33650 | [(S)-1-((S)-1-Carbamoyl-2-phenyl-eth...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050652(CHEMBL47146 | PD-160946 | [(R)-2-(2-Fluoro-phenyl)...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was tested for binding affinity towards NK1 binding sites in human lymphoma IM9 cells using [125I]Bolton-Hunter as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050641(CHEMBL45340 | PD-161182 | [(R)-2-(2,3-Difluoro-phe...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compound was tested for binding affinity towards NK1 binding sites in human lymphoma IM9 cells using [125I]Bolton-Hunter substrate P as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50050668(CHEMBL45278 | [(R)-1-Methyl-2-phenyl-1-((S)-1-phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article