Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50034804
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285138(2-{1-[1-(1-{3-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285150(2-{1-[1-(1-{3-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285149(2-{1-[1-(1-{2-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285133(Ac-dBHG-Arg-Asp-Ile-Ile-Trp-OH | CHEMBL411965)
Affinity DataIC50:  3nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285140(2-{1-[1-(1-{2-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50366384(CHEMBL1790448)
Affinity DataIC50:  4nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285137(2-{1-[1-(1-{5-amino-1-[10,11-dihydro-5H-dibenzo[a,...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285157(2-{1-[1-(1-{3-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285125(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285148(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  5nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285135((S)-3-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285156(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285153(2-{1-[1-(2-carboxy-1-{1-[2-(10,11-dihydro-5H-diben...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285146(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  8nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285134(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50032181(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  8nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285146(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285141(Ac-dBHG-Tyr-Asp-Ile-Ile-Trp-OH | CHEMBL405916)
Affinity DataIC50:  11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285132(4-[2-carboxy-1-(1-{1-[1-carboxy-2-(1H-3-indolyl)et...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285124(Ac-dBHG-Trp-Asp-Ile-Ile-Trp-OH | CHEMBL409180)
Affinity DataIC50:  11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285152(2-{1-[1-(2-carboxy-1-{2-carboxy-1-[10,11-dihydro-5...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285131(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285130((S)-3-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50:  18nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285136((S)-3-{2-[(R)-2-Acetylamino-2-(10,11-dihydro-5H-di...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285128(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285147(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285151((S)-3-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50:  30nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285145(2-{1-[2-carbamoyl-1-(2-carboxy-1-{1-[10,11-dihydro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285139(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  40nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285158((S)-4-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50:  48nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285155(Ac-dBHG-His-Asp-Ile-Ile-Trp-OH | CHEMBL408616)
Affinity DataIC50:  50nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285127((S)-2-{(2S,3S)-2-[2-((S)-2-{(S)-2-[(R)-2-Acetylami...)
Affinity DataIC50:  120nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285126((S)-2-{(2S,3S)-2-[2-(2-{(S)-2-[(R)-2-Acetylamino-2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285143((S)-2-{(2S,3S)-2-[2-((S)-2-{(S)-2-[(R)-2-Acetylami...)
Affinity DataIC50:  180nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50366385(CHEMBL1790451)
Affinity DataIC50:  350nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50285142((S)-2-{(S)-2-[2-((S)-2-{(S)-2-[(R)-2-Acetylamino-2...)
Affinity DataIC50:  380nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article