Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50034804
TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285138BDBM50285138(2-{1-[1-(1-{3-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285150BDBM50285150(2-{1-[1-(1-{3-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285149BDBM50285149(2-{1-[1-(1-{2-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285133BDBM50285133(Ac-dBHG-Arg-Asp-Ile-Ile-Trp-OH | CHEMBL411965)
Affinity DataIC50: 3nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285140BDBM50285140(2-{1-[1-(1-{2-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285137BDBM50285137(2-{1-[1-(1-{5-amino-1-[10,11-dihydro-5H-dibenzo[a,...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366384BDBM50366384(CHEMBL1790448)
Affinity DataIC50: 4nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285125BDBM50285125(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285157BDBM50285157(2-{1-[1-(1-{3-carbamoyl-1-[10,11-dihydro-5H-dibenz...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285148BDBM50285148(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 5nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285156BDBM50285156(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285135BDBM50285135((S)-3-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285153BDBM50285153(2-{1-[1-(2-carboxy-1-{1-[2-(10,11-dihydro-5H-diben...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285134BDBM50285134(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285146BDBM50285146(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032181BDBM50032181(3-{2-[2-Acetylamino-2-(10,11-dihydro-5H-dibenzo[a,...)
Affinity DataIC50: 8nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285146BDBM50285146(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 8nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285124BDBM50285124(Ac-dBHG-Trp-Asp-Ile-Ile-Trp-OH | CHEMBL409180)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285141BDBM50285141(Ac-dBHG-Tyr-Asp-Ile-Ile-Trp-OH | CHEMBL405916)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285152BDBM50285152(2-{1-[1-(2-carboxy-1-{2-carboxy-1-[10,11-dihydro-5...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285132BDBM50285132(4-[2-carboxy-1-(1-{1-[1-carboxy-2-(1H-3-indolyl)et...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285131BDBM50285131(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285130BDBM50285130((S)-3-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50: 18nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285136BDBM50285136((S)-3-{2-[(R)-2-Acetylamino-2-(10,11-dihydro-5H-di...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285128BDBM50285128(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285147BDBM50285147(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285151BDBM50285151((S)-3-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50: 30nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285139BDBM50285139(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 40nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285145BDBM50285145(2-{1-[2-carbamoyl-1-(2-carboxy-1-{1-[10,11-dihydro...)
Affinity DataIC50: 40nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285158BDBM50285158((S)-4-{(S)-2-[(R)-2-Acetylamino-2-(10,11-dihydro-5...)
Affinity DataIC50: 48nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285155BDBM50285155(Ac-dBHG-His-Asp-Ile-Ile-Trp-OH | CHEMBL408616)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against ET-A from porcine heart membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285127BDBM50285127((S)-2-{(2S,3S)-2-[2-((S)-2-{(S)-2-[(R)-2-Acetylami...)
Affinity DataIC50: 120nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285126BDBM50285126((S)-2-{(2S,3S)-2-[2-(2-{(S)-2-[(R)-2-Acetylamino-2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285143BDBM50285143((S)-2-{(2S,3S)-2-[2-((S)-2-{(S)-2-[(R)-2-Acetylami...)
Affinity DataIC50: 180nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366385BDBM50366385(CHEMBL1790451)
Affinity DataIC50: 350nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285142BDBM50285142((S)-2-{(S)-2-[2-((S)-2-{(S)-2-[(R)-2-Acetylamino-2...)
Affinity DataIC50: 380nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article