Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50034835
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251742BDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 4.20nMAssay Description:compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287108BDBM50287108((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287103BDBM50287103((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287107BDBM50287107((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)
Affinity DataIC50: 65nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251742BDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287102BDBM50287102((S)-2-(2-{[1-((S)-2-Benzyloxycarbonylamino-4-methy...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287111BDBM50287111((S)-2-(2-{[1-((S)-6-Amino-2-benzyloxycarbonylamino...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287103BDBM50287103((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50: 320nMAssay Description:compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287099BDBM50287099((S)-2-(3-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50: 370nMAssay Description:Compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287110BDBM50287110((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50: 390nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287101BDBM50287101((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287100BDBM50287100((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287105BDBM50287105((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287101BDBM50287101((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)
Affinity DataIC50: 800nMAssay Description:compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287106BDBM50287106((S)-2-{2-[(1-Benzyloxycarbonylamino-2-naphthalen-2...)
Affinity DataIC50: 3.30E+3nMAssay Description:Compound was tested for inhibitory activity against Endothelin-converting enzyme isolated from guinea pig lung membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287109BDBM50287109((S)-2-{2-[(1-Benzyloxycarbonylamino-2-methyl-propy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287104BDBM50287104((S)-2-{2-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287104BDBM50287104((S)-2-{2-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article