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Found 18 Enz. Inhib. hit(s) with all data for entry = 50034835
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  4.20nMAssay Description:compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287108((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287103((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287107((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)
Affinity DataIC50:  65nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287102((S)-2-(2-{[1-((S)-2-Benzyloxycarbonylamino-4-methy...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287111((S)-2-(2-{[1-((S)-6-Amino-2-benzyloxycarbonylamino...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287103((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50:  320nMAssay Description:compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287099((S)-2-(3-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50:  370nMAssay Description:Compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287110((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50:  390nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287101((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287100((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287105((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287101((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)
Affinity DataIC50:  800nMAssay Description:compound was tested for inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287106((S)-2-{2-[(1-Benzyloxycarbonylamino-2-naphthalen-2...)
Affinity DataIC50:  3.30E+3nMAssay Description:Compound was tested for inhibitory activity against Endothelin-converting enzyme isolated from guinea pig lung membrane.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287109((S)-2-{2-[(1-Benzyloxycarbonylamino-2-methyl-propy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287104((S)-2-{2-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287104((S)-2-{2-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails Article