Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50034915
TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50142887BDBM50142887(1-tert-Butyl-3-(4-chloro-phenyl)-1H-pyrazolo[3,4-d...)
Affinity DataIC50: 4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3289BDBM3289(N-benzyl-6,7-dimethoxyquinazolin-4-amine | CHEMBL5...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25116BDBM25116(cid_1400 | CHEMBL306380 | 1-tert-butyl-3-(4-methyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291091BDBM50291091(4-(3-Chloro-phenylsulfanyl)-6,7-dimethoxy-quinazol...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366492BDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 17nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291080BDBM50291080(4-(3-Chloro-phenoxy)-6,7-dimethoxy-quinazoline | C...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3531BDBM3531(CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3532BDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3263BDBM3263(CHEMBL329672 | N-(3-chlorophenyl)quinazolin-4-amin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3530BDBM3530(6,7-dimethoxy-N-phenylquinazolin-4-amine | CHEMBL5...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227519BDBM50227519(CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291082BDBM50291082((6-Methoxy-quinazolin-4-yl)-(3,4,5-trimethoxy-phen...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291090BDBM50291090(CHEMBL1191611 | CHEMBL542733 | (6,7-Dimethoxy-quin...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290835BDBM50290835(CHEMBL100714 | CHEMBL544833 | (3,4-Dimethoxy-pheny...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6497BDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6497BDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50: 500nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291098BDBM50291098((6,7-Dimethoxy-quinazolin-4-yl)-indan-5-yl-amine; ...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291080BDBM50291080(4-(3-Chloro-phenoxy)-6,7-dimethoxy-quinazoline | C...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291077BDBM50291077((6,7-Dimethoxy-quinazolin-4-yl)-(4-morpholin-4-yl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291094BDBM50291094((6-Chloro-quinazolin-4-yl)-(3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291091BDBM50291091(4-(3-Chloro-phenylsulfanyl)-6,7-dimethoxy-quinazol...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227519BDBM50227519(CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291097BDBM50291097((3,5-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273281BDBM50273281(CHEMBL456375 | CHEMBL543669 | N-methyl-4-anilino-6...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291100BDBM50291100(6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenoxy)-quinazo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3532BDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3531BDBM3531(CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290835BDBM50290835(CHEMBL100714 | CHEMBL544833 | (3,4-Dimethoxy-pheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291082BDBM50291082((6-Methoxy-quinazolin-4-yl)-(3,4,5-trimethoxy-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291090BDBM50291090(CHEMBL1191611 | CHEMBL542733 | (6,7-Dimethoxy-quin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3530BDBM3530(6,7-dimethoxy-N-phenylquinazolin-4-amine | CHEMBL5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291084BDBM50291084((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)-(3,4,5-trimetho...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291097BDBM50291097((3,5-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291088BDBM50291088((2-Chloro-6,7-dimethoxy-quinazolin-4-yl)-(3,4,5-tr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291085BDBM50291085((3,4,5-Trimethoxy-phenyl)-(6,7,8-trimethoxy-quinaz...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3289BDBM3289(N-benzyl-6,7-dimethoxyquinazolin-4-amine | CHEMBL5...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291096BDBM50291096((6,8-Dimethyl-quinazolin-4-yl)-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3263BDBM3263(CHEMBL329672 | N-(3-chlorophenyl)quinazolin-4-amin...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291098BDBM50291098((6,7-Dimethoxy-quinazolin-4-yl)-indan-5-yl-amine; ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291099BDBM50291099(4-(3,4-Dimethoxy-phenylsulfanyl)-6,7-dimethoxy-qui...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291099BDBM50291099(4-(3,4-Dimethoxy-phenylsulfanyl)-6,7-dimethoxy-qui...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation, 0.05-0.10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291083BDBM50291083((9H-Purin-6-yl)-(3,4,5-trimethoxy-phenyl)-amine; h...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291094BDBM50291094((6-Chloro-quinazolin-4-yl)-(3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273281BDBM50273281(CHEMBL456375 | CHEMBL543669 | N-methyl-4-anilino-6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291085BDBM50291085((3,4,5-Trimethoxy-phenyl)-(6,7,8-trimethoxy-quinaz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291077BDBM50291077((6,7-Dimethoxy-quinazolin-4-yl)-(4-morpholin-4-yl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291096BDBM50291096((6,8-Dimethyl-quinazolin-4-yl)-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291088BDBM50291088((2-Chloro-6,7-dimethoxy-quinazolin-4-yl)-(3,4,5-tr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article