Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50034916
TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.316nMAssay Description:Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystok...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 1.30nMAssay Description:Tested for the 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataEC50:  2nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072427(2-[2,4-Dioxo-5-phenyl-3-(3-phenyl-ureido)-2,3,4,5-...)
Affinity DataIC50: 25nMAssay Description:Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystok...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072427(2-[2,4-Dioxo-5-phenyl-3-(3-phenyl-ureido)-2,3,4,5-...)
Affinity DataIC50: 50nMAssay Description:Tested for the 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450536(CHEMBL357983)
Affinity DataEC50:  110nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450537(CHEMBL146206)
Affinity DataEC50:  210nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450536(CHEMBL357983)
Affinity DataIC50: 251nMAssay Description:Tested for the 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450535(CHEMBL421778)
Affinity DataEC50:  300nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450535(CHEMBL421778)
Affinity DataIC50: 1.59E+3nMAssay Description:Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystok...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450537(CHEMBL146206)
Affinity DataIC50: 1.59E+3nMAssay Description:Tested for the 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072427(2-[2,4-Dioxo-5-phenyl-3-(3-phenyl-ureido)-2,3,4,5-...)
Affinity DataEC50:  1.60E+3nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450535(CHEMBL421778)
Affinity DataIC50: 3.16E+3nMAssay Description:Tested for the 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50215056(CHEMBL346160)
Affinity DataEC50:  5.60E+3nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450537(CHEMBL146206)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystok...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450536(CHEMBL357983)
Affinity DataIC50: 3.16E+4nMAssay Description:Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystok...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article