Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50037320
LigandChemical structure of BindingDB Monomer ID 50370403BDBM50370403(CHEMBL177829)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM of [3H](+)-PENT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50370403BDBM50370403(CHEMBL177829)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM of [3H](+)-DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370391BDBM50370391(CHEMBL175813)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370408BDBM50370408(CHEMBL177435)
Affinity DataIC50: 6.70nMAssay Description:In vitro binding affinity against angiotensin II AT-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370394BDBM50370394(CHEMBL368791)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370404BDBM50370404(CHEMBL175930)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370404BDBM50370404(CHEMBL175930)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370394BDBM50370394(CHEMBL368791)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028866BDBM50028866(N-[(1S,2R)-2-(4-Hydroxy-phenyl)-indan-1-yl]-2,2-di...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370397BDBM50370397(CHEMBL177556)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370397BDBM50370397(CHEMBL177556)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370400BDBM50370400(CHEMBL176264)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370405BDBM50370405(PD-123177 | CHEMBL535139)
Affinity DataIC50: 66nMAssay Description:In vitro binding affinity against angiotensin II AT-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370392BDBM50370392(CHEMBL369712)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370398BDBM50370398(CHEMBL175211)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370402BDBM50370402(CHEMBL441498)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target3-dehydroquinate synthase(Escherichia coli (strain K12))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028881BDBM50028881((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...)
Affinity DataKi:  220nMAssay Description:Compound was evaluated for its inhibitory constant against 3-dehydroquinate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50409932BDBM50409932(CHEMBL178537)
Affinity DataKi:  250nMAssay Description:Compound was tested for inhibitory activity against FK506 binding protein 12 (FKBP12)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35714BDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370395BDBM50370395(CHEMBL175411)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370391BDBM50370391(CHEMBL175813)
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370400BDBM50370400(CHEMBL176264)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35714BDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028868BDBM50028868(N-[2-(4-Amino-phenyl)-1-phenyl-ethyl]-2,2-diphenyl...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50030448BDBM50030448(CHEMBL269732 | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards recombinant FK506 binding protein 12 to determine the FKBP binding property of the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028880BDBM50028880((3S,4R)-3-Ethyl-4-phenyl-3-(3-phenyl-propyl)-1-(2,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005944BDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVasopressin V2 receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370399BDBM50370399(CHEMBL360272)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028888BDBM50028888((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-(3-phe...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028877BDBM50028877((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-phenyl...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370402BDBM50370402(CHEMBL441498)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370410BDBM50370410(CHEMBL369660)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370399BDBM50370399(CHEMBL360272)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370409BDBM50370409(CHEMBL332150)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370407BDBM50370407(CHEMBL49500)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370395BDBM50370395(CHEMBL175411)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370396BDBM50370396(CHEMBL178591)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370398BDBM50370398(CHEMBL175211)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028867BDBM50028867(SCH-48461 | (3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028867BDBM50028867(SCH-48461 | (3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed