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Found 11 Enz. Inhib. hit(s) with all data for entry = 50042207
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421360(CHEMBL358119 | SB-207058)
Affinity DataIC50:  0.0250nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataIC50:  0.0800nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421359(CHEMBL145075)
Affinity DataIC50:  0.100nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422085(CHEMBL142490)
Affinity DataIC50:  0.100nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421362(CHEMBL143862)
Affinity DataIC50:  0.160nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421361(CHEMBL143426)
Affinity DataIC50:  0.5nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM85026(N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...)
Affinity DataIC50:  0.630nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422086(CHEMBL142621)
Affinity DataIC50:  7.90nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422083(CHEMBL356546)
Affinity DataIC50:  16nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422087(CHEMBL422116)
Affinity DataIC50:  79nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422084(CHEMBL146386)
Affinity DataIC50:  200nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed