Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 526
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3386BDBM3386(7-[2-(1H-Imidazol-l-yl)-5-methylimidazo[1,5-b]pyri...)
Affinity DataIC50: 0.600nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3383BDBM3383(7-[5-methyl-2-(pyrrolidin-1-yl)imidazo[1,5-a]pyrid...)
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3385BDBM3385(7-[5-methyl-2-(1H-pyrrol-1-yl)imidazo[1,5-a]pyrida...)
Affinity DataIC50: 80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3379BDBM3379(7-[5-Methyl-2-(methylthio)imidazo[1,5-b]pyridazin-...)
Affinity DataIC50: 80nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3388BDBM3388(7-[5-methyl-2-(1H-1,2,4-triazol-1-yl)imidazo[1,5-a...)
Affinity DataIC50: 100nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3392BDBM3392(7-[5-methyl-2-(5-methyl-1H-imidazol-1-yl)imidazo[1...)
Affinity DataIC50: 100nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3395BDBM3395(7-[2-(1H-imidazol-1-yl)-5-methylimidazo[1,5-a]pyri...)
Affinity DataIC50: 230nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3382BDBM3382(7-[2-(dimethylamino)-5-methylimidazo[1,5-a]pyridaz...)
Affinity DataIC50: 270nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3374BDBM3374(7-{2-chloroimidazo[1,5-a]pyridazin-7-yl}-1-phenylh...)
Affinity DataIC50: 340nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3373BDBM3373(( 1RS)-2-Chloro-5-methyl-alpha-phenyl-7-imidazo[1,...)
Affinity DataIC50: 380nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3393BDBM3393(7-[5-methyl-2-(4-methyl-1H-imidazol-1-yl)imidazo[1...)
Affinity DataIC50: 550nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3377BDBM3377(7-(5-Methylimidazo[1,5-b]pyridazin-7-yl)-l-phenyl-...)
Affinity DataIC50: 560nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3389BDBM3389(7-[5-methyl-2-(1H-1,2,3-triazol-1-yl)imidazo[1,5-a...)
Affinity DataIC50: 640nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3378BDBM3378(7-{2-methoxy-5-methylimidazo[1,5-a]pyridazin-7-yl}...)
Affinity DataIC50: 640nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3365BDBM3365(7-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-...)
Affinity DataIC50: 840nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3391BDBM3391(7-[5-methyl-2-(2H-1,2,3-triazol-2-yl)imidazo[1,5-a...)
Affinity DataIC50: 1.30E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3363BDBM3363(5-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}p...)
Affinity DataIC50: 1.30E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3375BDBM3375(7-{2-chloro-5-ethylimidazo[1,5-a]pyridazin-7-yl}-1...)
Affinity DataIC50: 2.00E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3364BDBM3364(7-[5-(benzyloxy)pentyl]-2-chloro-5-methylimidazo[1...)
Affinity DataIC50: 2.30E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3394BDBM3394(7-[5-methyl-2-(2-methyl-1H-imidazol-1-yl)imidazo[1...)
Affinity DataIC50: 2.50E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3390BDBM3390(7-[5-methyl-2-(4H-1,2,4-triazol-4-yl)imidazo[1,5-a...)
Affinity DataIC50: 2.60E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3380BDBM3380(7-{2-amino-5-methylimidazo[1,5-a]pyridazin-7-yl}-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3369BDBM3369(8-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-...)
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3381BDBM3381(7-[5-methyl-2-(methylamino)imidazo[1,5-a]pyridazin...)
Affinity DataIC50: 3.40E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3387BDBM3387(7-[5-methyl-2-(1H-pyrazol-1-yl)imidazo[1,5-a]pyrid...)
Affinity DataIC50: 3.40E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3367BDBM3367(7-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-...)
Affinity DataIC50: 3.90E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3368BDBM3368(6-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-...)
Affinity DataIC50: 4.80E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3384BDBM3384(7-[5-methyl-2-(piperidin-1-yl)imidazo[1,5-a]pyrida...)
Affinity DataIC50: 6.70E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3366BDBM3366(2-chloro-5-methyl-7-(7-phenylheptyl)imidazo[1,5-a]...)
Affinity DataIC50: 1.40E+4nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3372BDBM3372(5-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}p...)
Affinity DataIC50: 2.20E+4nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3370BDBM3370(5-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}p...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3371BDBM3371(5-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}p...)
Affinity DataIC50: 1.10E+5nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandChemical structure of BindingDB Monomer ID 3376BDBM3376(7-[2-chloro-5-(propan-2-yl)imidazo[1,5-a]pyridazin...)
Affinity DataIC50: 1.10E+5nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2005
Entry Details Article
PubMed