Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50004912
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030004BDBM50030004(1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030012BDBM50030012(1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030026BDBM50030026((8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030019BDBM50030019(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011247BDBM50011247(S-(-)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthale...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030025BDBM50030025(1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013016BDBM50013016(CHEMBL26835 | 7-Dipropylamino-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030010BDBM50030010((8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030027BDBM50030027((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030001BDBM50030001(Trifluoro-methanesulfonic acid 7-dipropylamino-5,6...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030016BDBM50030016((8-Ethynyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  4nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030002BDBM50030002((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029999BDBM50029999((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030005BDBM50030005(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  6nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030024BDBM50030024((8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipr...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030003BDBM50030003(Trifluoro-methanesulfonic acid 7-dipropylamino-5,6...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029998BDBM50029998((8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipr...)
Affinity DataKi:  12nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030020BDBM50030020((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  16nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029997BDBM50029997((8-Ethynyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  16nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030009BDBM50030009(Dipropyl-(R)-1,2,3,4-tetrahydro-naphthalen-2-yl-am...)
Affinity DataKi:  17nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030013BDBM50030013(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  19nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030006BDBM50030006(1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1...)
Affinity DataKi:  19nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030017BDBM50030017((8-Ethynyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  22nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030028BDBM50030028((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  23nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030000BDBM50030000((8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipr...)
Affinity DataKi:  24nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030022BDBM50030022((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  25nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030007BDBM50030007(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  26nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030014BDBM50030014(((R)-8-Methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  34nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50020582BDBM50020582(CHEMBL284820 | Dipropyl-(1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  37nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030023BDBM50030023(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  37nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030015BDBM50030015((8-Methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipr...)
Affinity DataKi:  42nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030021BDBM50030021(Dipropyl-(S)-1,2,3,4-tetrahydro-naphthalen-2-yl-am...)
Affinity DataKi:  56nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030011BDBM50030011((8-Methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipr...)
Affinity DataKi:  62nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030008BDBM50030008((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  130nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030018BDBM50030018(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi: >300nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed