Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50004931
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030232BDBM50030232((S)-((S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50: 0.480nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030236BDBM50030236((S)-((S)-8-Benzhydryl-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataIC50: 0.920nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030238BDBM50030238((S)-((S)-11-Benzhydryl-1-aza-tricyclo[5.4.0.0*3,9*...)
Affinity DataIC50: 1.90nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030230BDBM50030230((S)-((S)-9-Benzhydryl-1-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataIC50: 2.40nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030228BDBM50030228((S)-((S)-3-Benzhydryl-octahydro-2,5-methano-isoqui...)
Affinity DataIC50: 3.30nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030241BDBM50030241((S)-((S)-9-Benzhydryl-8-aza-tricyclo[5.3.1.0*3,8*]...)
Affinity DataIC50: 4.10nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030233BDBM50030233((S)-((S)-8-Benzhydryl-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataIC50: 7.10nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030237BDBM50030237((S)-((S)-9-Benzhydryl-4-oxa-8-aza-tricyclo[5.3.1.0...)
Affinity DataIC50: 7.20nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030231BDBM50030231((S)-((S)-3-Benzhydryl-octahydro-2,5-methano-isoqui...)
Affinity DataIC50: 39nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030234BDBM50030234((S)-((S)-9-Benzhydryl-8-aza-tricyclo[5.3.1.0*3,8*]...)
Affinity DataIC50: 58nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030226BDBM50030226((S)-((S)-8-Benzhydryl-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataIC50: 68nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030235BDBM50030235((S)-((S)-9-Benzhydryl-8-aza-tricyclo[5.3.1.0*3,8*]...)
Affinity DataIC50: 170nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030239BDBM50030239((S)-((S)-3-Benzhydryl-octahydro-2,5-methano-isoqui...)
Affinity DataIC50: 230nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030227BDBM50030227((S)-((S)-8-Benzhydryl-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataIC50: 1.10E+3nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030240BDBM50030240((S)-((S)-9-Benzhydryl-8-aza-tricyclo[5.3.1.0*3,8*]...)
Affinity DataIC50: 4.40E+3nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030229BDBM50030229((S)-((S)-3-Benzhydryl-octahydro-2,5-methano-isoqui...)
Affinity DataIC50: 4.80E+3nMAssay Description:Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed