Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50036338
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031555BDBM50031555((S)-3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propion...)
Affinity DataIC50: 50nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031545BDBM50031545((S)-3-Benzo[1,3]dioxol-5-yl-3-[3-(4-carbamimidoyl-...)
Affinity DataIC50: 52nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031565BDBM50031565((S)-3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propion...)
Affinity DataIC50: 67nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031553BDBM50031553(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 101nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031559BDBM50031559(3-Benzo[1,3]dioxol-5-yl-3-[3-(4-carbamimidoyl-phen...)
Affinity DataIC50: 104nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031561BDBM50031561(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 108nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031544BDBM50031544(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 115nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031547BDBM50031547(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 122nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031556BDBM50031556((Aminobenzamidino)succinyl analogue | (S)-3-[3-(4-...)
Affinity DataIC50: 133nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031556BDBM50031556((Aminobenzamidino)succinyl analogue | (S)-3-[3-(4-...)
Affinity DataIC50: 133nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031563BDBM50031563(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 158nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031550BDBM50031550(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 170nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031557BDBM50031557(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 224nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031554BDBM50031554(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 256nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031552BDBM50031552(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 294nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031539BDBM50031539(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 302nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031540BDBM50031540(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 321nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031558BDBM50031558(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 491nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031566BDBM50031566(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 580nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031551BDBM50031551(3-[5-(4-Carbamimidoyl-phenyl)-pent-4-enoylamino]-p...)
Affinity DataIC50: 904nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031564BDBM50031564(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031546BDBM50031546(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031548BDBM50031548({amino[4-(3-{[(2S)-1-carboxybut-3-en-2-yl]carbamoy...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031538BDBM50031538(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-buty...)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031542BDBM50031542(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-4-ph...)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031541BDBM50031541(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-3-ph...)
Affinity DataIC50: 4.88E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031562BDBM50031562(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031543BDBM50031543(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-prop...)
Affinity DataIC50: 5.88E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Searle Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031549BDBM50031549(3-[4-(4-Carbamimidoyl-phenylamino)-butyrylamino]-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed