Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50036346
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032410(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032410(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032406(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032404(6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-...)
Affinity DataKi:  1.57nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032404(6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032407((3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032411(8-Fluoro-6,11-dimethyl-3-(3-methyl-butyl)-1,2,3,4,...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032408(CHEMBL419343 | N-(3-Benzyl-6,11-dimethyl-1,2,3,4,5...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032416(CHEMBL317354 | N-(3-Benzyl-6,11-dimethyl-1,2,3,4,5...)
Affinity DataKi:  10nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032412(3-Benzyl-6,11-dimethyl-1,3,4,5,6,7-hexahydro-2H-2,...)
Affinity DataKi:  11nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032405(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  18.4nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032405(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  18.4nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032417(3-Benzyl-8-bromo-6,11-dimethyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  19nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032401(3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  19.6nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032401(3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  20nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032409(8-Fluoro-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2...)
Affinity DataKi:  30.5nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032409(8-Fluoro-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2...)
Affinity DataKi:  31nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50407300(CHEMBL397705)
Affinity DataKi:  37nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032415(3-Benzyl-8-chloro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  40nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032415(3-Benzyl-8-chloro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  40.1nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032401(3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  43nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032401(3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  43nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032409(8-Fluoro-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2...)
Affinity DataKi:  51.8nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032409(8-Fluoro-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2...)
Affinity DataKi:  52nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032411(8-Fluoro-6,11-dimethyl-3-(3-methyl-butyl)-1,2,3,4,...)
Affinity DataKi:  56nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50009063((+)3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6...)
Affinity DataKi:  60nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032402(3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-me...)
Affinity DataKi:  83nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50407300(CHEMBL397705)
Affinity DataKi:  83.1nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032413(3-Benzyl-8-iodo-6,11-dimethyl-1,2,3,4,5,6-hexahydr...)
Affinity DataKi:  131nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032407((3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-...)
Affinity DataKi:  258nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032404(6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-...)
Affinity DataKi:  295nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032415(3-Benzyl-8-chloro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  381nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032415(3-Benzyl-8-chloro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  381nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032414(3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano...)
Affinity DataKi:  482nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032405(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  487nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032405(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  487nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032417(3-Benzyl-8-bromo-6,11-dimethyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  501nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032412(3-Benzyl-6,11-dimethyl-1,3,4,5,6,7-hexahydro-2H-2,...)
Affinity DataKi:  691nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032406(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  832nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032408(CHEMBL419343 | N-(3-Benzyl-6,11-dimethyl-1,2,3,4,5...)
Affinity DataKi:  1.41E+3nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  1.54E+3nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032410(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  1.71E+3nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032410(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  1.71E+3nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032416(CHEMBL317354 | N-(3-Benzyl-6,11-dimethyl-1,2,3,4,5...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032413(3-Benzyl-8-iodo-6,11-dimethyl-1,2,3,4,5,6-hexahydr...)
Affinity DataKi:  2.04E+3nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50367062(METAZOCINE)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50009063((+)3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed