Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50005081
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032410(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032422(3-Benzyl-7-chloro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  1.72nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032426(3-Benzyl-7-bromo-6,11-dimethyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  1.75nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032425(7-Bromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,...)
Affinity DataKi:  2.49nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032423(7-Chloro-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2...)
Affinity DataKi:  2.62nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity of the compound was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032418(9-Iodo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,3...)
Affinity DataKi:  35.2nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032418(9-Iodo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,3...)
Affinity DataKi:  35.2nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50407300(CHEMBL397705)
Affinity DataKi:  37nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032419(3-Benzyl-9-bromo-6,11-dimethyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  68.6nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032420(3-Benzyl-7,9-dibromo-6,11-dimethyl-1,2,3,4,5,6-hex...)
Affinity DataKi:  70.6nMAssay Description:Binding affinity of the compound was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032421(3-Benzyl-7,9-dichloro-6,11-dimethyl-1,2,3,4,5,6-he...)
Affinity DataKi:  71.5nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50407300(CHEMBL397705)
Affinity DataKi:  83.1nMAssay Description:Binding affinity of the compound was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032418(9-Iodo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,3...)
Affinity DataKi:  94nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032418(9-Iodo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,3...)
Affinity DataKi:  94nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032427(7,9-Dibromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-...)
Affinity DataKi:  120nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032428(9-Bromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,...)
Affinity DataKi:  144nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032428(9-Bromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,...)
Affinity DataKi:  144nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032427(7,9-Dibromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-...)
Affinity DataKi:  211nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032424(3-Benzyl-9-iodo-6,11-dimethyl-1,2,3,4,5,6-hexahydr...)
Affinity DataKi:  231nMAssay Description:Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032425(7-Bromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,...)
Affinity DataKi:  283nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032426(3-Benzyl-7-bromo-6,11-dimethyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  346nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032428(9-Bromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,...)
Affinity DataKi:  365nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032428(9-Bromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,...)
Affinity DataKi:  365nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032424(3-Benzyl-9-iodo-6,11-dimethyl-1,2,3,4,5,6-hexahydr...)
Affinity DataKi:  597nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032422(3-Benzyl-7-chloro-6,11-dimethyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  764nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032419(3-Benzyl-9-bromo-6,11-dimethyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  1.22E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  1.54E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032410(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  1.71E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032420(3-Benzyl-7,9-dibromo-6,11-dimethyl-1,2,3,4,5,6-hex...)
Affinity DataKi:  2.01E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032421(3-Benzyl-7,9-dichloro-6,11-dimethyl-1,2,3,4,5,6-he...)
Affinity DataKi:  2.17E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032423(7-Chloro-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2...)
Affinity DataKi:  4.96E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed