Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50005103
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032850([3-([3,3']Bithiophenyl-5-ylmethoxy)-benzyl]-((E)-6...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[(6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-amin...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032853(2-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032856(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032830({3-[(Dimethyl-o-tolyl-silanyl)-methoxy]-benzyl}-et...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032837(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032847(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032848((6,6-Dimethyl-hepta-2,4-diynyl)-{3-[(dimethyl-o-to...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032834(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032832(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032842({3-[(Benzyl-dimethyl-silanyl)-methoxy]-benzyl}-((E...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032840(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(2-...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032844(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032835((3-{[(4-Bromo-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032831((3-{[(4-Chloro-phenyl)-dimethyl-silanyl]-methoxy}-...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032851(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50: 870nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032833(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032839(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032854(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032855(1-{4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-eth...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032845(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032838(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032846(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032841(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032849(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032852({3-[(Cyclohexyl-dimethyl-silanyl)-methoxy]-benzyl}...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed