Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 426
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2278(3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2284(5-chloro-3-(phenylsulfanyl)-1H-indole-2-carboxamid...)
Affinity DataIC50:  14nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2287(5-chloro-N-methyl-3-(phenylsulfanyl)-1H-indole-2-c...)
Affinity DataIC50:  22nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2288(3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  23nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1317(3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...)
Affinity DataIC50:  36nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2279(2-[(benzenesulfinyl)methyl]-3-(phenylsulfanyl)-1H-...)
Affinity DataIC50:  63nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2278(3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  71nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataIC50:  101nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2280(2-[(benzenesulfinyl)methyl]-5-chloro-3-(phenylsulf...)
Affinity DataIC50:  112nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2278(3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  116nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2283(5Cl3PhS-2IndolCONH2 inhibitor 9b | methyl 5-chloro...)
Affinity DataIC50:  156nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  311nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1317(3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...)
Affinity DataIC50:  545nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2286(5Cl3PhS-2IndolCONH2 inhibitor 12 | N-methyl-3-(phe...)
Affinity DataIC50:  746nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2284(5-chloro-3-(phenylsulfanyl)-1H-indole-2-carboxamid...)
Affinity DataIC50:  1.04E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1437(5-methoxyindole-2-carboxylic acid [N -[3-(aminoeth...)
Affinity DataIC50:  1.32E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2288(3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  1.39E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2284(5-chloro-3-(phenylsulfanyl)-1H-indole-2-carboxamid...)
Affinity DataIC50:  1.46E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2282(5Cl3PhS-2IndolCONH2 inhibitor 9a | cid_454848 | me...)
Affinity DataIC50:  2.50E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2279(2-[(benzenesulfinyl)methyl]-3-(phenylsulfanyl)-1H-...)
Affinity DataIC50:  2.57E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2288(3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  2.76E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2279(2-[(benzenesulfinyl)methyl]-3-(phenylsulfanyl)-1H-...)
Affinity DataIC50:  2.99E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  7.32E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataIC50:  1.13E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1317(3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...)
Affinity DataIC50:  2.50E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1437(5-methoxyindole-2-carboxylic acid [N -[3-(aminoeth...)
Affinity DataIC50:  3.34E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  3.95E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataIC50:  5.79E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2281(3-(benzenesulfinyl)-2-[(benzenesulfinyl)methyl]-1H...)
Affinity DataIC50:  7.28E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2285(5Cl3PhS-2IndolCONH2 inhibitor 11 | N,N-dimethyl-3-...)
Affinity DataIC50:  8.76E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed