Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 341
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 771BDBM771(CHEMBL16584 | 3-[cyclopropyl(phenyl)methyl]-4-hydr...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 784BDBM784(5,6,7,8,9,1O-Hexahydro-4-hydroxy-3-(2-methyl-nylpr...)
Affinity DataKi:  22nM ΔG°:  -43.3kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 783BDBM783(4-hydroxy-3-(1-phenylbutyl)-2H,5H,6H,7H,8H,9H,10H-...)
Affinity DataKi:  29nM ΔG°:  -42.6kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 789BDBM789(3-(dicyclopropylmethyl)-4-hydroxy-2H,5H,6H,7H,8H,9...)
Affinity DataKi:  57nM ΔG°:  -40.9kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 786BDBM786(5,6,7,8,9,10-Hexahydroro-4-hydroxy- 1-phenylpentyl...)
Affinity DataKi:  62nM ΔG°:  -40.7kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 782BDBM782(4-hydroxy-3-(1-phenylpropyl)-2H,5H,6H,7H,8H,9H,10H...)
Affinity DataKi:  75nM ΔG°:  -40.3kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 787BDBM787(5,6,7,8,9,1O-Hexahydro-4-hydroxy-3-(3-methyl- l-ph...)
Affinity DataKi:  90nM ΔG°:  -39.8kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 788BDBM788(3-(Diphenylmethyl)-5,6,7,8,9,1O-hexahydro-4-hydrox...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 781BDBM781(4-hydroxy-3-(1-phenylethyl)-2H,5H,6H,7H,8H,9H,10H-...)
Affinity DatapH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 790BDBM790(3-benzyl-4-hydroxy-2H,5H,6H,7H,8H,9H,10H-cycloocta...)
Affinity DatapH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 791BDBM791(4-hydroxy-3-(2-phenylethyl)-2H,5H,6H,7H,8H,9H,10H-...)
Affinity DatapH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 792BDBM792(4-hydroxy-3-(3-phenylpropyl)-2H,5H,6H,7H,8H,9H,10H...)
Affinity DatapH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed