Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50005274
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035051BDBM50035051(1-(2-Methyl-benzo[1,4]dioxin-5-yl)-piperazine | CH...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035047BDBM50035047(1-(6-Fluoro-benzofuran-7-yl)-piperazine | CHEMBL61...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035059BDBM50035059(1-Benzo[b]thiophen-7-yl-piperazine | CHEMBL60809)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035056BDBM50035056(1-Benzo[1,4]dioxin-5-yl-piperazine | CHEMBL434784)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035048BDBM50035048(1-(2-Methyl-benzofuran-7-yl)-piperazine | CHEMBL61...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035042BDBM50035042(1-Benzofuran-7-yl-piperazine | CHEMBL61032)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007407BDBM50007407(CHEMBL277120 | 1-NP | 1-Naphthalen-1-yl-piperazine...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035063BDBM50035063(1-(4-Fluoro-benzofuran-7-yl)-piperazine | CHEMBL30...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035064BDBM50035064(1-(5-Methoxy-benzofuran-7-yl)-piperazine | CHEMBL5...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035043BDBM50035043(1-(5-Bromo-benzofuran-7-yl)-piperazine | CHEMBL301...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035057BDBM50035057(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine |...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035044BDBM50035044(1-(3-Methyl-benzofuran-7-yl)-piperazine | CHEMBL30...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035055BDBM50035055(1-(5,6,7,8-Tetrahydro-naphthalen-1-yl)-piperazine ...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035041BDBM50035041(1-(5-Fluoro-benzofuran-7-yl)-piperazine | CHEMBL43...)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035060BDBM50035060(1-(5-Methyl-benzofuran-7-yl)-piperazine | CHEMBL29...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035053BDBM50035053(1-(3-Bromo-benzofuran-7-yl)-piperazine | CHEMBL593...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035049BDBM50035049(1-(6-Nitro-benzofuran-7-yl)-piperazine | CHEMBL621...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001862BDBM50001862(CHEMBL9666 | 2-METHOXYPHENYLPIPERAZINE | 4-(2-Meth...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035062BDBM50035062(7-Piperazin-1-yl-1H-indole | CHEMBL60803)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035050BDBM50035050(1-(6-Chloro-2,3-dihydro-benzo[1,4]dioxin-5-yl)-pip...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035045BDBM50035045(7-Piperazin-1-yl-benzofuran-6-carbonitrile | CHEMB...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035052BDBM50035052(1-(4-Methyl-benzofuran-7-yl)-piperazine | CHEMBL59...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035061BDBM50035061(1-(4-Bromo-benzofuran-7-yl)-piperazine | CHEMBL585...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001917BDBM50001917(CHEMBL59597 | 1-(3-Methoxy-phenyl)-piperazine)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035046BDBM50035046(1-(4-Methoxy-benzofuran-7-yl)-piperazine | CHEMBL6...)
Affinity DataKi:  430nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001898BDBM50001898(CHEMBL9434 | 1-Phenyl-piperazine | PHENYLPIPERAZIN...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035058BDBM50035058(1-(2,3-Dimethoxy-phenyl)-piperazine | CHEMBL58963)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035054BDBM50035054(1-(6-Methoxy-2,3-dihydro-benzo[1,4]dioxin-5-yl)-pi...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001913BDBM50001913(4-METHOXYPHENYLPIPERAZINE | CHEMBL59517 | 1-(4-Met...)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed