Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50036301
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82517BDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035512BDBM50035512(N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  2.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86708BDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataIC50: 2.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035515BDBM50035515(N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  2.5nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035508BDBM50035508(CHEMBL29027 | p-MPPI | 4-Iodo-N-{2-[4-(2-methoxy-p...)
Affinity DataKi:  2.60nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035513BDBM50035513(CHEMBL286607 | CHEMBL1775000 | 4-Fluoro-N-{2-[4-(2...)
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035510BDBM50035510(4-Chloromethyl-N-{2-[4-(2-methoxy-phenyl)-piperazi...)
Affinity DataKi:  3.5nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035518BDBM50035518(4-Ethyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  9.30nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035514BDBM50035514(N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035525BDBM50035525(4-Amino-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035524BDBM50035524(4-Butyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047471BDBM50047471(N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035511BDBM50035511(N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  16nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035516BDBM50035516(4-Amino-3-iodo-N-{2-[4-(2-methoxy-phenyl)-piperazi...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035521BDBM50035521(4-(2-Chloro-acetylamino)-N-{2-[4-(2-methoxy-phenyl...)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035517BDBM50035517(4-Azido-3-iodo-N-{2-[4-(2-methoxy-phenyl)-piperazi...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035519BDBM50035519(4-tert-Butyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  27nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035523BDBM50035523(4-Hexyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  58nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035520BDBM50035520(N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  75nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035509BDBM50035509(4-Heptyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  82nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed