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Found
675
Enz. Inhib. hit(s) with all data for entry = 4906
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ic50
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ki
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kcal/mole
Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Ki: 0.00620nM
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Target
5-hydroxytryptamine receptor 1B
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Ki: 0.0200nM
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Target
5-hydroxytryptamine receptor 1B
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
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Ki: 0.0300nM
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Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM81497
(CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...)
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Ki: 0.0400nM
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Target
5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21393
(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
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Ki: 0.0600nM
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Target
5-hydroxytryptamine receptor 1D
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Ki: 0.0600nM
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Target
5-hydroxytryptamine receptor 1D
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
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Ki: 0.0700nM
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Target
5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.120nM
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Target
5-hydroxytryptamine receptor 1D
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Ki: 0.130nM
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Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.140nM
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Target
5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.150nM
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Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Ki: 0.190nM
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Target
5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50005127
(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
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Ki: 0.230nM
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Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.25nM
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Target
5-hydroxytryptamine receptor 4
(Guinea pig)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM29525
(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
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Ki: 0.25nM
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Target
5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Ki: 0.260nM
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Target
5-hydroxytryptamine receptor 1B
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM81499
(NSC_155346 | CYANOPINDOLOL | CAS_155346 | CYANOPIN...)
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Ki: 0.260nM
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Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
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Ki: 0.260nM
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Target
5-hydroxytryptamine receptor 4
(Guinea pig)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM29525
(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
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Ki: 0.310nM
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Target
5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.330nM
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Target
5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.340nM
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Target
5-hydroxytryptamine receptor 1B
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.350nM
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Target
5-hydroxytryptamine receptor 1B
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM81498
(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
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Ki: 0.360nM
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5-hydroxytryptamine receptor 1D
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.370nM
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5-hydroxytryptamine receptor 6
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Ki: 0.380nM
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Target
5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Ki: 0.380nM
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5-hydroxytryptamine receptor 2A
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Ki: 0.390nM
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5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM22867
(3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...)
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Ki: 0.400nM
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Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Ki: 0.510nM
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Target
5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.520nM
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Target
5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM22867
(3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...)
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Ki: 0.520nM
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Target
5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Ki: 0.570nM
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Target
5-hydroxytryptamine receptor 1B
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Ki: 0.570nM
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5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
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Ki: 0.570nM
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5-hydroxytryptamine receptor 1D
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Ki: 0.580nM
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5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50044418
(FLESINOXAN | CHEMBL69326 | 4-Fluoro-N-{2-[4-(2-hyd...)
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Ki: 0.600nM
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5-hydroxytryptamine receptor 1D
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM30704
(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
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Ki: 0.600nM
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5-hydroxytryptamine receptor 2A
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Ki: 0.600nM
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5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Ki: 0.600nM
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5-hydroxytryptamine receptor 1D
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM50016479
(CHEMBL160976 | LYSERGOL | CHEMBL39947 | cid_14987 ...)
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Ki: 0.630nM
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5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM82367
(CAS_141533-35-9 | SDZ 216-525 | SDZ 216,525)
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Ki: 0.660nM
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5-hydroxytryptamine receptor 1D
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Ki: 0.700nM
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Ki: 0.700nM
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5-hydroxytryptamine receptor 7
(Rat)
University of Alberta
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PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Ki: 0.700nM
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5-hydroxytryptamine receptor 1B
(Human)
University of Alberta
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PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
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Ki: 0.75nM
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5-hydroxytryptamine receptor 1D
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM30704
(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
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Ki: 0.770nM
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5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Affinity Data
Ki: 0.790nM
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5-hydroxytryptamine receptor 2A
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM28582
([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
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Ki: 0.790nM
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5-hydroxytryptamine receptor 1A
(Human)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM21393
(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
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Ki: 0.810nM
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Target
5-hydroxytryptamine receptor 1B
(Rat)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
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Ki: 0.810nM
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