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Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50036315
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16496(2-{3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4...)
Affinity DataIC50:  4.40nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50009777((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040782((2,8-Diisopropyl-3-thioxo-2,3-dihydro-benzo[1,4]ox...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040781((2,7-Difluoro-9H-fluoren-9-yl)-acetic acid | CHEMB...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040779((2-Fluoro-9H-fluoren-9-yl)-acetic acid | CHEMBL349...)
Affinity DataIC50:  850nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16415((1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040780(CHEMBL163958 | cid_234512 | spiro[9H-fluorene-9,4'...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50034798((9H-Fluoren-9-yl)-acetic acid | CHEMBL44381)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040777(CHEMBL351278 | spiro[9H-fluorene-9,4'-(tetrahydro-...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040783((2,7-Difluoro-fluoren-9-ylidene)-acetic acid | CHE...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040784(CHEMBL422030 | [2-Fluoro-fluoren-(9E)-ylidene]-ace...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50034811(9H-Fluorene-9-carboxylic acid | CHEMBL295321)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040778(5-(9H-Fluoren-9-yl)-1H-tetrazole | CHEMBL164508)
Affinity DataIC50:  2.17E+5nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040785(5-(9H-Fluoren-9-ylmethyl)-1H-tetrazole | CHEMBL353...)
Affinity DataIC50:  1.49E+6nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed