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Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50005803
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029577(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041160(CHEMBL16285 | N-(2-{2-[1-(4-Chloro-benzyl)-4-methy...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041156(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041173(CHEMBL277746 | N-(2-{2-[1-(4-Chloro-benzyl)-4-meth...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029577(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041171((R)-2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041154(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041162(3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041169(1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridin-2...)
Affinity DataIC50:  60nMAssay Description:Tested against 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041165(3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041161(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50:  75nMAssay Description:Tested for activity against 5-Lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041168(3-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50:  105nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041170((S)-2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041164(3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041155(2-({2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041159(2-(Acetyl-{2-[1-(4-chloro-benzyl)-4-methyl-6-(5-ph...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  3.50E+3nMAssay Description:Tested for activity against 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50041172(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed