Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50005803
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029577BDBM50029577(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041156BDBM50041156(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041160BDBM50041160(N-(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029577BDBM50029577(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041173BDBM50041173(N-(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041171BDBM50041171((R)-2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041154BDBM50041154(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041162BDBM50041162(3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041169BDBM50041169(1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridin-2...)
Affinity DataIC50: 60nMAssay Description:Tested against 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041165BDBM50041165(3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041161BDBM50041161(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 75nMAssay Description:Tested for activity against 5-Lipoxygenase (5-LO)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041168BDBM50041168(3-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 105nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041170BDBM50041170((S)-2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041164BDBM50041164(3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041155BDBM50041155(2-({2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041159BDBM50041159(2-(Acetyl-{2-[1-(4-chloro-benzyl)-4-methyl-6-(5-ph...)
Affinity DataIC50: 900nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 3.50E+3nMAssay Description:Tested for activity against 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041172BDBM50041172(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of human 5-Lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed