Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50006001
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043607BDBM50043607(1-(Adamantane-2-carbonyl)-9a,11a-dimethyl-1,2,3,3a...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043608BDBM50043608(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039257BDBM50039257((1S,9aR,11aS)-9a,11a-Dimethyl-1-(3-methyl-butyryl)...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039298BDBM50039298(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039268BDBM50039268((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039259BDBM50039259((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043605BDBM50043605(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039294BDBM50039294((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025356BDBM50025356(4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039295BDBM50039295(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043612BDBM50043612(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039302BDBM50039302(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043611BDBM50043611(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039285BDBM50039285((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039284BDBM50039284(9a,11a-Dimethyl-1-(thiomorpholine-4-carbonyl)-1,2,...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039308BDBM50039308((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039287BDBM50039287((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043606BDBM50043606(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039266BDBM50039266((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043610BDBM50043610(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043607BDBM50043607(1-(Adamantane-2-carbonyl)-9a,11a-dimethyl-1,2,3,3a...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039293BDBM50039293(9a,11a-Dimethyl-1-(morpholine-4-carbonyl)-1,2,3,3a...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039268BDBM50039268((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039257BDBM50039257((1S,9aR,11aS)-9a,11a-Dimethyl-1-(3-methyl-butyryl)...)
Affinity DataKi:  9nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043608BDBM50043608(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039295BDBM50039295(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  14nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039302BDBM50039302(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039294BDBM50039294((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039259BDBM50039259((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039298BDBM50039298(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043604BDBM50043604(17-tert-Butylcarbamoyl-10,13-dimethyl-2,7,8,9,10,1...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039260BDBM50039260(9a,11a-Dimethyl-1-(piperazine-1-carbonyl)-1,2,3,3a...)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043605BDBM50043605(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  75nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039266BDBM50039266((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  150nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025356BDBM50025356(4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043612BDBM50043612(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  190nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043611BDBM50043611(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  360nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039284BDBM50039284(9a,11a-Dimethyl-1-(thiomorpholine-4-carbonyl)-1,2,...)
Affinity DataKi:  570nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043606BDBM50043606(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  720nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039308BDBM50039308((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  750nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039285BDBM50039285((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  820nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039293BDBM50039293(9a,11a-Dimethyl-1-(morpholine-4-carbonyl)-1,2,3,3a...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039287BDBM50039287((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043604BDBM50043604(17-tert-Butylcarbamoyl-10,13-dimethyl-2,7,8,9,10,1...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043610BDBM50043610(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039260BDBM50039260(9a,11a-Dimethyl-1-(piperazine-1-carbonyl)-1,2,3,3a...)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after pre-incubation for 10 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed