Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with all data for entry = 50006175
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045643BDBM50045643(3-[1-(4-Chloro-benzyl)-4-methyl-6-(quinolin-2-ylme...)
Affinity DataIC50: 3nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045673BDBM50045673(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 3nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041161BDBM50041161(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 8nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045679BDBM50045679(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 11nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045654BDBM50045654(N-{4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 11nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045663BDBM50045663(4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 12nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045640BDBM50045640(3-[1-(4-Chloro-benzyl)-6-(5-methoxy-pyridin-2-ylme...)
Affinity DataIC50: 12nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045657BDBM50045657(2,2-Dimethyl-3-[4-methyl-6-(5-phenyl-pyridin-2-ylm...)
Affinity DataIC50: 16nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045673BDBM50045673(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 16nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041161BDBM50041161(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 16nMAssay Description:Tested for inhibition of 5-HPETE production by rat 5-LO; value ranges from 16-36 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041161BDBM50041161(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 17nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045647BDBM50045647(5-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 19nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045643BDBM50045643(3-[1-(4-Chloro-benzyl)-4-methyl-6-(quinolin-2-ylme...)
Affinity DataIC50: 19nMAssay Description:Tested for inhibition of leukotriene biosynthesis by binding to 5-lipoxygenase activating proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045663BDBM50045663(4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 20nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045664BDBM50045664(3-[1-(4-Chloro-benzyl)-6-(isoquinolin-3-ylmethoxy)...)
Affinity DataIC50: 20nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045667BDBM50045667(L-689065 | 3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-ph...)
Affinity DataIC50: 22nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045638BDBM50045638(4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 23nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045637BDBM50045637(2,2-Dimethyl-3-[4-methyl-1-(3-phenyl-propyl)-6-(5-...)
Affinity DataIC50: 23nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045653BDBM50045653(3-[1-(4-Chloro-benzyl)-4-methyl-6-(6-phenyl-pyridi...)
Affinity DataIC50: 27nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045669BDBM50045669(3-[1-(3-Methoxy-benzyl)-4-methyl-6-(5-phenyl-pyrid...)
Affinity DataIC50: 28nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045666BDBM50045666(3-[1-(4-Chloro-benzyl)-4-methyl-6-(thiophen-2-ylme...)
Affinity DataIC50: 28nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045675BDBM50045675(3-[1-(4-Methoxy-benzyl)-4-methyl-6-(5-phenyl-pyrid...)
Affinity DataIC50: 28nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045657BDBM50045657(2,2-Dimethyl-3-[4-methyl-6-(5-phenyl-pyridin-2-ylm...)
Affinity DataIC50: 30nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045652BDBM50045652(3-[1-Cyclohexylmethyl-4-methyl-6-(5-phenyl-pyridin...)
Affinity DataIC50: 33nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045678BDBM50045678(3-[1-(4-Chloro-benzyl)-4-ethyl-6-(5-phenyl-pyridin...)
Affinity DataIC50: 33nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045637BDBM50045637(2,2-Dimethyl-3-[4-methyl-1-(3-phenyl-propyl)-6-(5-...)
Affinity DataIC50: 35nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045646BDBM50045646(3-[1-(4-Chloro-benzyl)-4-methyl-6-(pyridin-2-ylmet...)
Affinity DataIC50: 35nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045652BDBM50045652(3-[1-Cyclohexylmethyl-4-methyl-6-(5-phenyl-pyridin...)
Affinity DataIC50: 35nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045654BDBM50045654(N-{4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 36nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045660BDBM50045660([1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridin-...)
Affinity DataIC50: 37nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045677BDBM50045677(3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50: 38nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045640BDBM50045640(3-[1-(4-Chloro-benzyl)-6-(5-methoxy-pyridin-2-ylme...)
Affinity DataIC50: 40nMAssay Description:Tested for inhibition of leukotriene biosynthesis by binding to 5-lipoxygenase activating proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045675BDBM50045675(3-[1-(4-Methoxy-benzyl)-4-methyl-6-(5-phenyl-pyrid...)
Affinity DataIC50: 40nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045669BDBM50045669(3-[1-(3-Methoxy-benzyl)-4-methyl-6-(5-phenyl-pyrid...)
Affinity DataIC50: 40nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045672BDBM50045672(3-[6-(5-Butyl-pyridin-2-ylmethoxy)-1-(4-chloro-ben...)
Affinity DataIC50: 42nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045656BDBM50045656(2,2-Dimethyl-3-[4-methyl-6-(5-phenyl-pyridin-2-ylm...)
Affinity DataIC50: 45nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045658BDBM50045658(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 46nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045667BDBM50045667(L-689065 | 3-[1-(4-Chloro-benzyl)-4-methyl-6-(5-ph...)
Affinity DataIC50: 60nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045670BDBM50045670(3-[1-(4-Chloro-benzyl)-6-(5-cyano-pyridin-2-ylmeth...)
Affinity DataIC50: 66nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045639BDBM50045639(N-{4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 67nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041161BDBM50041161(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 75nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045674BDBM50045674(3-[1-(4-Chloro-benzyl)-4-methyl-6-(4-phenyl-pyridi...)
Affinity DataIC50: 80nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045676BDBM50045676(3-[1-(4-Chloro-benzyl)-4,4-dimethyl-6-(5-phenyl-py...)
Affinity DataIC50: 88nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045645BDBM50045645(3-[1-Butyl-4-methyl-6-(5-phenyl-pyridin-2-ylmethox...)
Affinity DataIC50: 95nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045680BDBM50045680(1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridin-2...)
Affinity DataIC50: 97nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045659BDBM50045659(3-[1-(4-Chloro-benzyl)-6-(5-phenyl-pyridin-2-ylmet...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045646BDBM50045646(3-[1-(4-Chloro-benzyl)-4-methyl-6-(pyridin-2-ylmet...)
Affinity DataIC50: 110nMAssay Description:Tested for inhibition of leukotriene biosynthesis by binding to 5-lipoxygenase activating proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045656BDBM50045656(2,2-Dimethyl-3-[4-methyl-6-(5-phenyl-pyridin-2-ylm...)
Affinity DataIC50: 110nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045679BDBM50045679(1-(4-Chloro-benzyl)-2-[2,2-dimethyl-3-(1H-tetrazol...)
Affinity DataIC50: 120nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045639BDBM50045639(N-{4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)
Affinity DataIC50: 125nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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