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Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50006219
TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046234(2-Amino-7-benzyl-3,4a,5,7a-tetrahydro-pyrrolo[3,2-...)
Affinity DataKi:  12nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046239(2-Amino-9-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)
Affinity DataKi:  15nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)
Affinity DataKi:  45nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)
Affinity DataKi:  90nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046234(2-Amino-7-benzyl-3,4a,5,7a-tetrahydro-pyrrolo[3,2-...)
Affinity DataKi:  100nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046226(2-Amino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046227(2-Amino-6-thiophen-2-ylmethyl-3,7-dihydro-pyrrolo[...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046231(2-Amino-6-furan-2-ylmethyl-3,7-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  0.0570nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046249(2-Amino-6-thiophen-3-ylmethyl-3,7-dihydro-pyrrolo[...)
Affinity DataIC50:  0.0670nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046239(2-Amino-9-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)
Affinity DataIC50:  0.0670nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046252(2-Amino-6-benzyl-3,7-dihydro-pyrrolo[3,2-d]pyrimid...)
Affinity DataIC50:  0.0850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046224(2-Amino-8-[(thiophen-3-ylmethyl)-amino]-1,9-dihydr...)
Affinity DataIC50:  0.0850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046229(2-Amino-6-pyridin-3-yl-3,7-dihydro-pyrrolo[3,2-d]p...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046246(2-Amino-8-[(thiophen-2-ylmethyl)-amino]-1,9-dihydr...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046241(2-Amino-8-[(furan-2-ylmethyl)-amino]-1,9-dihydro-p...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046251(2-Amino-8-benzylamino-1,9-dihydro-purin-6-one | CH...)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046221(2-Amino-6-[(thiophen-3-ylmethyl)-amino]-3,7-dihydr...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046238(2,8-Diamino-9-thiophen-3-ylmethyl-1,9-dihydro-puri...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046216(2-Amino-6-[(furan-2-ylmethyl)-amino]-3,7-dihydro-p...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046223(2-Amino-6-benzylamino-3,7-dihydro-pyrrolo[3,2-d]py...)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046243(2-Amino-6-[(thiophen-2-ylmethyl)-amino]-3,7-dihydr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046248(2-Amino-8-[(3-methyl-thiophen-2-ylmethyl)-amino]-1...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046218(2-Amino-6-[(3-methyl-thiophen-2-ylmethyl)-amino]-3...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046226(2-Amino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046236(2-Amino-8-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046254(2-Amino-8-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046225(2-Amino-7-(3,4-dichloro-benzyl)-3,5-dihydro-pyrrol...)
Affinity DataIC50:  17nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046230(2-Amino-8-furan-2-ylmethyl-1,9-dihydro-purin-6-one...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042804(2-Amino-7-(3-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046242(2-Amino-7-thiophen-2-ylmethyl-3,5-dihydro-pyrrolo[...)
Affinity DataIC50:  21nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046255(2-Amino-8-(pyridin-3-ylamino)-1,9-dihydro-purin-6-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046245(2-Amino-7-(4-iodo-benzyl)-3,5-dihydro-pyrrolo[3,2-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046233(2-Amino-7-(3-fluoro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039542(2-Amino-7-pyridin-3-ylmethyl-3,5-dihydro-pyrrolo[3...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)
Affinity DataIC50:  25nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046219(2-Amino-7-(4-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  25nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046217(2-Amino-8-benzyl-1,9-dihydro-purin-6-one | CHEMBL1...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046232(2-Amino-7-(3-trifluoromethyl-benzyl)-3,5-dihydro-p...)
Affinity DataIC50:  36nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046235(2-Amino-8-(3-methyl-thiophen-2-ylmethyl)-1,9-dihyd...)
Affinity DataIC50:  48nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046250(2-Amino-6-(3-methyl-thiophen-2-ylmethyl)-3,7-dihyd...)
Affinity DataIC50:  48nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039547(2-Amino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyrimid...)
Affinity DataIC50:  51nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046222(2-Amino-7-(3-methyl-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  57nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046247(2-Amino-8-pyridin-3-yl-1,9-dihydro-purin-6-one | C...)
Affinity DataIC50:  57nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046213(2-Amino-7-(3-hydroxy-benzyl)-3,5-dihydro-pyrrolo[3...)
Affinity DataIC50:  70nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)
Affinity DataIC50:  80nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046214(2-Amino-7-(3-methoxy-benzyl)-3,5-dihydro-pyrrolo[3...)
Affinity DataIC50:  82nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046240(2-Amino-7-furan-2-ylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  83nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046253(2-Amino-7-(2-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046244(2-Amino-7-(3-phenoxy-benzyl)-3,5-dihydro-pyrrolo[3...)
Affinity DataIC50:  147nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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