Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 315
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 386BDBM386((3S)-oxan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-...)
Affinity DataIC50: 0.0300nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 387BDBM387((3R)-oxan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-...)
Affinity DataIC50: 0.0300nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 383BDBM383((3S)-oxolan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-...)
Affinity DataIC50: 0.0300nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 384BDBM384((3R)-oxolan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-...)
Affinity DataIC50: 0.0300nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1030BDBM1030(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(1...)
Affinity DataIC50: 0.300nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 385BDBM385(cyclopentyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(...)
Affinity DataIC50: 0.330nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 388BDBM388(oxan-4-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(1S...)
Affinity DataIC50: 1.22nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 393BDBM393((3R)-3,6-dihydro-2H-pyran-3-yl N-[(2S,3R)-4-[(4aS,...)
Affinity DataIC50: 48.9nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 395BDBM395((3R)-oxan-3-yl N-[(2S,3R)-4-[(4aS,8aS)-3-(tert-but...)
Affinity DataIC50: 308nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 392BDBM392((3S)-3,6-dihydro-2H-pyran-3-yl N-[(2S,3R)-4-[(4aS,...)
Affinity DataIC50: 314nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 394BDBM394((3S)-oxan-3-yl N-[(2S,3R)-4-[(4aS,8aS)-3-(tert-but...)
Affinity DataIC50: 392nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 391BDBM391((3R)-oxolan-3-yl N-[(2S,3R)-4-[(4aS,8aS)-3-(tert-b...)
Affinity DataIC50: 694nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 389BDBM389(tert-butyl N-[(2S,3R)-4-[(4aS,8aS)-3-(tert-butylca...)
Affinity DataIC50: 3.00E+3nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2004
Entry Details Article
PubMed