Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50006242
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046613BDBM50046613(8-Allyl-7-propylamino-5,6,7,8-tetrahydro-naphthale...)
Affinity DataKi:  0.5nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046598BDBM50046598(8-Allyl-7-allylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  1nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046596BDBM50046596(Allyl-(1-allyl-8-methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  1.5nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21393BDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataKi:  1.60nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046615BDBM50046615((1-Allyl-8-methoxy-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi:  1.80nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046586BDBM50046586((2-Allylamino-8-methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  2nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046606BDBM50046606(8-Propyl-7-propylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  2.90nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046593BDBM50046593((1-Allyl-8-methoxy-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi:  2.90nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046599BDBM50046599(Allyl-(8-methoxy-1-methylene-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  3.80nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046589BDBM50046589((trans)-(1-Allyl-8-methoxy-1,2,3,4-tetrahydro-naph...)
Affinity DataKi:  4.10nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046600BDBM50046600([8-Methoxy-2-(methyl-propyl-amino)-1,2,3,4-tetrahy...)
Affinity DataKi:  5nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046590BDBM50046590((8-Methoxy-2-propylamino-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  5.40nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046592BDBM50046592((1-Allyl-8-methoxy-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi:  6.30nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046601BDBM50046601((8-Methoxy-1,3-dipropyl-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  7.60nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046602BDBM50046602(Cyclopropylmethyl-(1-cyclopropylmethyl-8-methoxy-1...)
Affinity DataKi:  8.5nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046603BDBM50046603((trans)-(1-Cyclopropylmethyl-8-methoxy-1,2,3,4-tet...)
Affinity DataKi:  9.30nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046619BDBM50046619(Allyl-(1-cyclopropylmethyl-8-methoxy-1,2,3,4-tetra...)
Affinity DataKi:  9.40nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046588BDBM50046588((trans)-Allyl-(1-allyl-8-methoxy-1,2,3,4-tetrahydr...)
Affinity DataKi:  10nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046605BDBM50046605(6,8-Dipropyl-7-propylamino-5,6,7,8-tetrahydro-naph...)
Affinity DataKi:  11nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046595BDBM50046595((8-Methoxy-1-propyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  11nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046611BDBM50046611((1-Cyclopropylmethyl-8-methoxy-1,2,3,4-tetrahydro-...)
Affinity DataKi:  15nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046608BDBM50046608((trans)-Allyl-(1-cyclopropylmethyl-8-methoxy-1,2,3...)
Affinity DataKi:  15nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046591BDBM50046591((trans)-(1-Allyl-8-methoxy-1,2,3,4-tetrahydro-naph...)
Affinity DataKi:  19nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046612BDBM50046612(2-Allylamino-8-methoxy-1,2,3,4-tetrahydro-naphthal...)
Affinity DataKi:  81nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046604BDBM50046604((trans)-(3-Allyl-8-methoxy-1,2,3,4-tetrahydro-naph...)
Affinity DataKi:  106nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046616BDBM50046616(Allyl-(1-allyl-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  152nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046597BDBM50046597((1-Allyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propy...)
Affinity DataKi:  174nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046594BDBM50046594((trans)-Allyl-(3-allyl-8-methoxy-1,2,3,4-tetrahydr...)
Affinity DataKi:  322nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046617BDBM50046617((trans)-Cyclopropylmethyl-(1-cyclopropylmethyl-8-m...)
Affinity DataKi:  642nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046618BDBM50046618((trans)-Allyl-(1-allyl-1,2,3,4-tetrahydro-naphthal...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046587BDBM50046587((trans)-(1-Allyl-1,2,3,4-tetrahydro-naphthalen-2-y...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046607BDBM50046607(Allyl-(3-allyl-8-methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046614BDBM50046614((3-Allyl-8-methoxy-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046584BDBM50046584((trans)-(1-Allyl-5-methoxy-1,2,3,4-tetrahydro-naph...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046585BDBM50046585((1-Allyl-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046610BDBM50046610((trans)-(2-Allylamino-8-methoxy-1,2,3,4-tetrahydro...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046609BDBM50046609((trans)-2-Allylamino-8-methoxy-1,2,3,4-tetrahydro-...)
Affinity DataKi: >1.00E+3nMAssay Description:In vivo binding affinity towards [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed