Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50006348
TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048044(2-Amino-7-(tetrahydro-thiophen-2-ylmethyl)-3,5-dih...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048045(2-Amino-7-[1,2]dithian-3-ylmethyl-3,5-dihydro-pyrr...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048046(2-Amino-7-(3-methyl-cyclohexylmethyl)-3,5-dihydro-...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048053(2-Amino-7-(3-trifluoromethyl-cyclohexylmethyl)-3,5...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039562(2-Amino-7-cyclopentylmethyl-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  29nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048043(2-Amino-7-cycloheptylmethyl-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048048(2-Amino-7-(tetrahydro-furan-2-ylmethyl)-3,5-dihydr...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048051(7-Adamantan-2-ylmethyl-2-amino-3,5-dihydro-pyrrolo...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048045(2-Amino-7-[1,2]dithian-3-ylmethyl-3,5-dihydro-pyrr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048044(2-Amino-7-(tetrahydro-thiophen-2-ylmethyl)-3,5-dih...)
Affinity DataIC50:  220nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048048(2-Amino-7-(tetrahydro-furan-2-ylmethyl)-3,5-dihydr...)
Affinity DataIC50:  300nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048053(2-Amino-7-(3-trifluoromethyl-cyclohexylmethyl)-3,5...)
Affinity DataIC50:  800nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048046(2-Amino-7-(3-methyl-cyclohexylmethyl)-3,5-dihydro-...)
Affinity DataIC50:  820nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048043(2-Amino-7-cycloheptylmethyl-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  860nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048049(2-Amino-7-piperidin-3-ylmethyl-3,5-dihydro-pyrrolo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048049(2-Amino-7-piperidin-3-ylmethyl-3,5-dihydro-pyrrolo...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048047(2-Amino-7-cyclohexyl-3,5-dihydro-pyrrolo[3,2-d]pyr...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039562(2-Amino-7-cyclopentylmethyl-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048050(2-Amino-7-cyclohex-1-enyl-3,5-dihydro-pyrrolo[3,2-...)
Affinity DataIC50:  1.90E+3nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048051(7-Adamantan-2-ylmethyl-2-amino-3,5-dihydro-pyrrolo...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048052(2,6-Diamino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048050(2-Amino-7-cyclohex-1-enyl-3,5-dihydro-pyrrolo[3,2-...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048047(2-Amino-7-cyclohexyl-3,5-dihydro-pyrrolo[3,2-d]pyr...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048052(2,6-Diamino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed