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Found 3 Enz. Inhib. hit(s) with all data for entry = 50036450
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17659((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...)
Affinity DataKi:  0.275nMAssay Description:Compound was tested for inhibition of the Folate hydrolaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048694(2-[(2-Carboxy-ethyl)-hydroxy-phosphinoylmethyl]-pe...)
Affinity DataKi:  1.90nMAssay Description:Compound was tested for inhibition of the Folate hydrolaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048693(2-Phosphonomethyl-succinic acid | 2-Phosphonomethy...)
Affinity DataKi:  700nMAssay Description:Compound was tested for inhibition of the Folate hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed