Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50006423
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048928BDBM50048928(4-(2,4-Dioxo-1-propyl-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: 5.00E+3nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048929BDBM50048929(4-(7-Methyl-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-...)
Affinity DataIC50: 5.00E+3nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048933BDBM50048933(4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50: 6.00E+3nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048931BDBM50048931(3-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50: 1.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048924BDBM50048924(5-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50: 1.10E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.20E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048943BDBM50048943(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: 1.20E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048925BDBM50048925(4-(1-Butyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl)...)
Affinity DataIC50: 1.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048932BDBM50048932(4-(2,4-Dioxo-1-pentyl-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: 1.60E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048935BDBM50048935(4-(5,7-Dioxo-4-propyl-4,5-dihydro-7H-[1,2,5]thiadi...)
Affinity DataIC50: 1.80E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048920BDBM50048920(4-[2,4-Dioxo-1-(tetrahydro-furan-3-yl)-1,4-dihydro...)
Affinity DataIC50: 1.90E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048948BDBM50048948(4-(1-Isobutyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-...)
Affinity DataIC50: 2.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048942BDBM50048942(4-(4-Methyl-5,7-dioxo-4,5-dihydro-7H-[1,2,5]thiadi...)
Affinity DataIC50: 2.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048938BDBM50048938((Z)-4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-...)
Affinity DataIC50: 2.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048940BDBM50048940(1-Hexyl-8-hydroxy-3-methyl-3,7,8,9-tetrahydro-puri...)
Affinity DataIC50: 5.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010981BDBM50010981(4-(3-Butoxy-4-methoxy-benzyl)-imidazolidin-2-one |...)
Affinity DataIC50: 5.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048939BDBM50048939(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-...)
Affinity DataIC50: 5.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048921BDBM50048921(4-(8-Bromo-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahyd...)
Affinity DataIC50: 6.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048927BDBM50048927(6-Heptyl-4-methyl-4H-[1,2,5]thiadiazolo[3,4-d]pyri...)
Affinity DataIC50: 7.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10850BDBM10850(1-(5-Oxohexyl)theobromine (pentoxifylline) | 3,7-d...)
Affinity DataIC50: 8.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048945BDBM50048945(4-(8-Mercapto-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetra...)
Affinity DataIC50: 1.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048922BDBM50048922(4-(6,7-Diethyl-1-methyl-2,4-dioxo-1,4-dihydro-2H-p...)
Affinity DataIC50: 1.30E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048934BDBM50048934(4-(1-Benzyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: 1.75E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048941BDBM50048941((3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin-1...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048926BDBM50048926(8-Mercapto-3-methyl-3,7-dihydro-purine-2,6-dione |...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048946BDBM50048946(4-(4-Methyl-5,7-dioxo-4,5-dihydro-7H-[1,2,5]thiadi...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048937BDBM50048937(4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048923BDBM50048923(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048947BDBM50048947(4-(2,4-Dioxo-1-propyl-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048950BDBM50048950(4-(8-Mercapto-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetra...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048936BDBM50048936(4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048930BDBM50048930(4-(8-Bromo-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahyd...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048944BDBM50048944(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048949BDBM50048949(4-(1-Methyl-2,4-dioxo-6-phenyl-1,4-dihydro-2H-pter...)
Affinity DataIC50: 2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed