Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50036416
TargetDihydrofolate reductase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50049156((2R,4R)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-me...)
Affinity DataIC50: 0.840nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 1.18nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50049154(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50049155(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed