Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 1210
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10045((2R,15S)-15-methyl-2-[2-(methylsulfanyl)ethyl]tetr...)
Affinity DataIC50: 12nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10046((2S,15S)-15-methyl-2-[2-(methylsulfanyl)ethyl]tetr...)
Affinity DataIC50: 22nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10044((2S,15S)-15-methyl-2-[(methylsulfanyl)methyl]tetra...)
Affinity DataIC50: 42nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10064(3,17-Dioxo-19-[(vinylthio)methyl]androsta-4,9(11)-...)
Affinity DataIC50: 50nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10069(3,17-Dioxo-19-[[(fluoromethyl)thio]methyl]androsta...)
Affinity DataIC50: 50nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10063((2R,15S)-15-methyl-2-[2-(prop-2-en-1-ylsulfanyl)et...)
Affinity DataIC50: 270nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10068(3,17-Dioxo-19-[(ethynylthio)methyl]androsta-4,9(11...)
Affinity DataIC50: 330nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10054(3,17-Dioxo-19-[(phenylthio)methyl]androsta-4,9(11)...)
Affinity DataIC50: 400nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10062(3,17-Dioxo-19-[[[(methylthio)methyl]thio]methyl]an...)
Affinity DataIC50: 570nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10047((2R,15S)-2-[2-(ethylsulfanyl)ethyl]-15-methyltetra...)
Affinity DataIC50: 870nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10053((2R,15S)-15-methyl-2-[2-(phenylselanyl)ethyl]tetra...)
Affinity DataIC50: 1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10056((2R,15S)-2-{2-[(2-hydroxyethyl)sulfanyl]ethyl}-15-...)
Affinity DataIC50: 1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10057((2R,15S)-2-{2-[(2-chloroethyl)sulfanyl]ethyl}-15-m...)
Affinity DataIC50: 1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10058(3,17-Dioxo-19-[[(2-mercaptoethyl)thio]methyl]andro...)
Affinity DataIC50: 1.00E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10059((2R,15S)-2-{2-[(difluoromethyl)sulfanyl]ethyl}-15-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10060((2R,15S)-2-{2-[(2,4-dinitrophenyl)disulfanyl]ethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10061((2R,15S)-15-methyl-2-[2-(prop-2-yn-1-ylsulfanyl)et...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10065(3,17-Dioxo-19-[[(methylthio)thio]methyl]androsta-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10066((2R,15S)-15-methyl-2-[2-(phenyldisulfanyl)ethyl]te...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10067((2R,15S)-2-[2-(cyclopropylsulfanyl)ethyl]-15-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10070(3,17-Dioxo-19-[(thiocyanato)methyl]androsta-4,9(11...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10071(3,17-Dioxo-19-[1,1-bis(methylthio)methyl]androsta-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10072((2R,15S)-2-[2,2-bis(ethylsulfanyl)ethyl]-15-methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10043(3,17-Dioxo-10-(methylthio)estra-4,9(11)-diene | (2...)
Affinity DataIC50: 7.40E+3nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10048(3,17-Dioxo-19-[(methylthio)ethyl]androsta-4,9(11)-...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10049(3,17-Dioxo-19-[(N,N-dimethylamino)methyl]androsta-...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10050((2R,15S)-2-(2-methoxyethyl)-15-methyltetracyclo[8....)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10051((2R,15S)-2-(2-iodoethyl)-15-methyltetracyclo[8.7.0...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10052(2-[(2R,15S)-15-methyl-5,14-dioxotetracyclo[8.7.0.0...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10055(3,17-Dioxo-19-[(acetylthio)methyl]androsta-4,9(11)...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed