Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 112 Enz. Inhib. hit(s) with all data for entry = 50006503
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050033(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  5.70nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050026(2-[(R)-1-{(S)-2-[(2,3-Dihydro-indole-1-carbonyl)-a...)
Affinity DataIC50:  5.90nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050043(5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-...)
Affinity DataIC50:  7.60nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050047(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050031(5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050032(2-[(R)-1-{(S)-2-[3-(2-Fluoro-phenyl)-ureido]-4-met...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050001(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050035(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050013(2-[(R)-1-[(S)-2-(3-Bicyclo[2.2.1]hept-2-yl-ureido)...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050013(2-[(R)-1-[(S)-2-(3-Bicyclo[2.2.1]hept-2-yl-ureido)...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050000(2-[(R)-1-{(S)-2-[(3,4-Dihydro-2H-quinoline-1-carbo...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049999(2-[(R)-1-[(S)-2-(3-Cyclopentyl-ureido)-4-methyl-pe...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050011(2-[(R)-1-{(S)-2-[(Indole-1-carbonyl)-amino]-4-meth...)
Affinity DataIC50:  58nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050024(2-[(R)-1-[(S)-2-(3-Cycloheptyl-ureido)-4-methyl-pe...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050016(2-[(R)-1-{(S)-2-[3-(3-Fluoro-phenyl)-ureido]-4-met...)
Affinity DataIC50:  66nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050002(5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-...)
Affinity DataIC50:  74nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050009(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050041(2-[(R)-1-{(S)-2-[3-(4-Hydroxy-cyclohexyl)-ureido]-...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050010(2-[(R)-1-{(S)-2-[3-(1-Methoxycarbonyl-cyclohexyl)-...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050034(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  141nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050045(5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-...)
Affinity DataIC50:  153nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050023(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050042(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050008(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050020(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50:  280nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050022(2-[(R)-1-[(S)-2-(3-Cyclopentyl-ureido)-4-methyl-pe...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050012(2-[(R)-1-[(S)-2-(3-Cycloheptyl-ureido)-4-methyl-pe...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050028(2-[(R)-1-[(S)-2-(3-Adamantan-2-yl-ureido)-4-methyl...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050038(2-[(R)-1-[(S)-2-(3-Bicyclo[2.2.1]hept-2-yl-ureido)...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050038(2-[(R)-1-[(S)-2-(3-Bicyclo[2.2.1]hept-2-yl-ureido)...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049983(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050003(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50:  620nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050025(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  650nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050007(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  660nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050029(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050021(2-[(R)-1-[(S)-2-(3-Adamantan-1-yl-ureido)-4-methyl...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050049(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  960nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050014(2-[(R)-1-[(S)-2-(3,3-Diethyl-ureido)-4-methyl-pent...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049981(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050036(({2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-m...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050039(2-[(R)-1-{(S)-2-[3-(4-Fluoro-phenyl)-ureido]-4-met...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050004(2-[(R)-1-[(S)-2-(3-Benzyl-ureido)-4-methyl-pentano...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050032(2-[(R)-1-{(S)-2-[3-(2-Fluoro-phenyl)-ureido]-4-met...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity was evaluated against ET- B Binding to Endothelin B receptor from porcine cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050030(2-[(R)-1-{(S)-2-[3-(4-Hydroxy-cyclohexyl)-ureido]-...)
Affinity DataIC50:  2.52E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050048(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050017(Azepane-1-carboxylic acid {(S)-1-[(R)-1-(4-hydroxy...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050037(2-[(R)-1-[(S)-2-(3,3-Diethyl-ureido)-4-methyl-pent...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050040(Azepane-1-carboxylic acid {(S)-1-[(R)-2-(1H-indol-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050005(5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-...)
Affinity DataIC50:  3.55E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050013(2-[(R)-1-[(S)-2-(3-Bicyclo[2.2.1]hept-2-yl-ureido)...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibitory activity was evaluated against ET- B Binding to Endothelin B receptor from porcine cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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