Compile Data Set for Download or QSAR
Report error Found 101 Enz. Inhib. hit(s) with all data for entry = 50006546
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050597BDBM50050597(1-Ethyl-3-methyl-6-(5-nitro-2-propoxy-phenyl)-1,5-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050584BDBM50050584(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050582BDBM50050582(N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050619BDBM50050619(3-Methyl-6-(2-propoxy-phenyl)-1-propyl-1,5-dihydro...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050605BDBM50050605([3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050627BDBM50050627(Thiophene-2-carboxylic acid [3-(1,3-dimethyl-4-oxo...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050626BDBM50050626(1-Ethyl-3-methyl-6-[5-(5-phenyl-1H-[1,2,4]triazol-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050603BDBM50050603(CHEMBL43862 | 1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydr ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050577BDBM50050577(1-Ethyl-3-methyl-6-[2-propoxy-5-(2-pyridin-3-yl-th...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050595BDBM50050595(1-Ethyl-3-methyl-6-[5-(4-methyl-thiazol-2-yl)-2-pr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050622BDBM50050622(1-Ethyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dihydro-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050579BDBM50050579([3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050620BDBM50050620(N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050618BDBM50050618([3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050580BDBM50050580(N-[3-(1-Ethyl-3-methyl-4-oxo-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050593BDBM50050593(1,3-Dimethyl-6-[5-(2-phenyl-thiazol-4-yl)-2-propox...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050611BDBM50050611(1,3-Dimethyl-6-[5-(2-methyl-thiazol-4-yl)-2-propox...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050590BDBM50050590(CHEMBL45039 | 1,3-Dimethyl-6-[5-(4-methyl-thiazol-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050585BDBM50050585(CHEMBL289701 | 1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050598BDBM50050598(N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050596BDBM50050596(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050610BDBM50050610(1-Ethyl-3-methyl-6-[5-(2-methyl-thiazol-4-yl)-2-pr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050614BDBM50050614(1-Ethyl-3-methyl-6-[5-(2-phenyl-thiazol-4-yl)-2-pr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050576BDBM50050576(1,3-Dimethyl-6-(2-propoxy-5-thiazol-2-yl-phenyl)-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050592BDBM50050592(CHEMBL46621 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050621BDBM50050621(CHEMBL42779 | 1,3-Dimethyl-6-[5-(2-morpholin-4-yl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050575BDBM50050575(1,3-Dimethyl-6-(5-nitro-2-propoxy-phenyl)-1,5-dihy...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050600BDBM50050600(N-[3-(1-Ethyl-3-methyl-4-oxo-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050624BDBM50050624(CHEMBL42776 | 6-(5-Dimethylamino-2-propoxy-phenyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050599BDBM50050599(1,3-Dimethyl-6-[5-(5-methyl-thiophen-2-yl)-2-propo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050581BDBM50050581(CHEMBL289344 | 1,3-Dimethyl-6-(2-propoxy-5-thiophe...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050602BDBM50050602(CHEMBL295224 | 6-[5-(5-Amino-1H-[1,2,4]triazol-3-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050615BDBM50050615(CHEMBL41004 | 6-(5-Dimethylamino-2-propoxy-phenyl)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050616BDBM50050616(CHEMBL42172 | 1-Butyl-3-methyl-6-(2-propoxy-phenyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050574BDBM50050574(3-Methyl-6-(2-propoxy-phenyl)-1-(2,2,2-trifluoro-e...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050617BDBM50050617(6-(5-Amino-2-propoxy-phenyl)-1-ethyl-3-methyl-1,5-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050607BDBM50050607(1,3-Dimethyl-6-(2-propoxy-phenyl)-1,5-dihydro-pyra...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050606BDBM50050606(CHEMBL295613 | 6-(5-Amino-2-propoxy-phenyl)-1,3-di...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050617BDBM50050617(6-(5-Amino-2-propoxy-phenyl)-1-ethyl-3-methyl-1,5-...)
Affinity DataEC50:  20nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050589BDBM50050589(1,3-Dimethyl-6-[5-(5-phenyl-1H-[1,2,4]triazol-3-yl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050588BDBM50050588(1-tert-Butyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dih...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050608BDBM50050608(6-(2-Ethoxy-phenyl)-1,3-dimethyl-1,5-dihydro-pyraz...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050583BDBM50050583(3-Methyl-6-(2-propoxy-phenyl)-5H-isothiazolo[3,4-d...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050580BDBM50050580(N-[3-(1-Ethyl-3-methyl-4-oxo-4,5-dihydro-1H-pyrazo...)
Affinity DataEC50:  30nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050584BDBM50050584(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataEC50:  40nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050603BDBM50050603(CHEMBL43862 | 1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydr ...)
Affinity DataEC50:  40nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050582BDBM50050582(N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataEC50:  40nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050612BDBM50050612(6-(2-Isopropoxy-phenyl)-1,3-dimethyl-1,5-dihydro-p...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050613BDBM50050613(2-(2-Propoxy-phenyl)-3H-pyrido[4,3-d]pyrimidin-4-o...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050596BDBM50050596(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataEC50:  50nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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