Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 902
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7031BDBM7031((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis(3-ac...)
Affinity DataKi:  0.0430nM ΔG°:  -61.6kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7034BDBM7034((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis(3-ac...)
Affinity DataKi:  0.0800nM ΔG°:  -59.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7033BDBM7033((4R,5S,6S,7R)-4,7-bis[(3,5-dimethoxyphenyl)methyl]...)
Affinity DataKi:  0.400nM ΔG°:  -55.8kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7066BDBM7066((4R,5S,6S,7R)-1,3-bis(cyclopropylmethyl)-5,6-dihyd...)
Affinity DataKi:  0.870nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7036BDBM7036((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7051BDBM7051((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7032BDBM7032((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis(4-fl...)
Affinity DataKi:  1.5nM ΔG°:  -52.4kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7045BDBM7045((4R,5S,6S,7R)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis({...)
Affinity DataKi:  2.5nM ΔG°:  -51.1kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7046BDBM7046((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  2.5nM ΔG°:  -51.1kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7070BDBM7070((4R,5S,6S,7R)-1,3-bis(cyclopropylmethyl)-4,7-bis[(...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7052BDBM7052((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7068BDBM7068((4R,5S,6S,7R)-1,3-bis(cyclopropylmethyl)-5,6-dihyd...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7037BDBM7037((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  3.40nM ΔG°:  -50.3kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7053BDBM7053((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7069BDBM7069((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(cyc...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7049BDBM7049((4R,5S,6S,7R)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis[(...)
Affinity DataKi:  4.70nM ΔG°:  -49.4kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7064BDBM7064((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(cyc...)
Affinity DataKi:  5.80nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7054BDBM7054(Substituted Cyclic Urea 43 | (4R,5S,6S,7R)-Hexahyd...)
Affinity DataKi:  7.10nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7044BDBM7044((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  8.40nM ΔG°:  -47.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7054BDBM7054(Substituted Cyclic Urea 43 | (4R,5S,6S,7R)-Hexahyd...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7050BDBM7050((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  8.60nM ΔG°:  -47.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7067BDBM7067((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(cyc...)
Affinity DataKi:  13nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7057BDBM7057((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  22nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7041BDBM7041((4R,5S,6S,7R)-1,3-dibenzyl-4,7-bis(cyclohexylmethy...)
Affinity DataKi:  28nM ΔG°:  -44.8kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7048BDBM7048((4R,5S,6S,7R)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis[(...)
Affinity DataKi:  35nM ΔG°:  -44.3kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7056BDBM7056((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  46nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7047BDBM7047((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  60nM ΔG°:  -42.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7065BDBM7065((4R,5S,6S,7R)-1,3-bis(cyclopropylmethyl)-5,6-dihyd...)
Affinity DataKi:  65nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7061BDBM7061((4R,5S,6S,7R)-1,3-bis(cyclopropylmethyl)-5,6-dihyd...)
Affinity DataKi:  86nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7058BDBM7058((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  160nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7062BDBM7062((4R,5S,6S,7R)-1,3-bis(cyclopropylmethyl)-5,6-dihyd...)
Affinity DataKi:  250nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7040BDBM7040((4R,5S,6S,7R)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis(1...)
Affinity DataKi:  580nM ΔG°:  -37.0kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7039BDBM7039((4R,5S,6S,7R)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis[2...)
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7038BDBM7038((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  1.70E+3nM ΔG°:  -34.3kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7063BDBM7063((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(cyc...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 7035BDBM7035((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(phe...)
Affinity DataKi:  5.00E+3nM ΔG°:  -31.5kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed