Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 1203
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9955BDBM9955((8S)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  3.10nM ΔG°:  -50.5kJ/mole IC50: 37nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
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Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9960BDBM9960((8R)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  5.30nM ΔG°:  -49.1kJ/mole IC50: 49nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9968BDBM9968((8R)-8-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  6nM ΔG°:  -48.8kJ/mole IC50: 50nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9981BDBM9981(CHEMBL71715 | 2,15-dimethyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  6.80nM IC50: 60nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9970BDBM9970((8R)-8-methoxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  12nM IC50: 130nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9967BDBM9967((8S)-8-methoxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  12nM ΔG°:  -47.0kJ/mole IC50: 120nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9956BDBM9956((8S)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  14nM ΔG°:  -46.6kJ/mole IC50: 110nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9966BDBM9966((8S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0^{2,7}....)
Affinity DataKi:  18nM ΔG°:  -46.0kJ/mole IC50: 160nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9965BDBM9965((8S)-8-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  21nM ΔG°:  -45.6kJ/mole IC50: 190nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9969BDBM9969((8R)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0^{2,7}....)
Affinity DataKi:  24nM IC50: 260nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9957BDBM9957((8S)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  30nM ΔG°:  -44.7kJ/mole IC50: 230nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9961BDBM9961((8R)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  43nM ΔG°:  -43.7kJ/mole IC50: 320nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9982BDBM9982((14S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,...)
Affinity DataKi:  45nM IC50: 360nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9962BDBM9962((8R)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  51nM ΔG°:  -43.3kJ/mole IC50: 440nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9976BDBM9976((8R)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  140nM IC50: 1.60E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9972BDBM9972((8S)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  180nM IC50: 1.30E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9977BDBM9977((8R)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  340nM IC50: 3.30E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9971BDBM9971((8S)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  380nM IC50: 3.70E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9958BDBM9958((8S)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/mole IC50: 9.00E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9963BDBM9963((8R)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  1.20E+3nM ΔG°:  -35.2kJ/mole IC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9964BDBM9964((8R)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  2.60E+3nM ΔG°:  -33.2kJ/mole IC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9973BDBM9973((8S)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  2.90E+3nM IC50: 1.40E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9959BDBM9959((8S)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  4.10E+3nM ΔG°:  -32.0kJ/mole IC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9978BDBM9978((8R)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  5.50E+3nM IC50: 4.30E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9974BDBM9974((8S)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  4.40E+4nM IC50: 5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9975BDBM9975((8S)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataIC50: 5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9979BDBM9979((8R)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  1.00E+5nM IC50: 5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandChemical structure of BindingDB Monomer ID 9980BDBM9980((8R)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataIC50: 5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2006
Entry Details Article
PubMed