Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50006643
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019293(1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-pipe...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataIC50:  490nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051985(CHEMBL288826 | N-[3-(4-Benzyl-piperidin-1-yl)-prop...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051984(CHEMBL36637 | N-[3-(4-Benzyl-piperazin-1-yl)-propy...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051979(CHEMBL35818 | N-{3-[4-(2-Oxo-2,3-dihydro-benzoimid...)
Affinity DataIC50:  720nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051978(2,2-Diphenyl-N-[3-(4-phenyl-piperidin-1-yl)-propyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051972(CHEMBL37974 | N-{3-[4-(2-Methoxy-phenyl)-piperazin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051968(CHEMBL37217 | N-[3-(Benzyl-methyl-amino)-propyl]-2...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051973(CHEMBL39907 | N-[3-(4-Phenoxy-piperidin-1-yl)-prop...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051976(CHEMBL36798 | N-[2-Methyl-3-(4-phenyl-piperidin-1-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051988(CHEMBL38095 | N-[3-(4-Hydroxy-4-phenyl-piperidin-1...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051975(CHEMBL40106 | N-[3-(2,6-Dimethyl-morpholin-4-yl)-p...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50043993(CHEMBL282833 | N-[3-(2,6-Dimethyl-piperidin-1-yl)-...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051986(CHEMBL40788 | N-(3-Diethylamino-propyl)-2,2-diphen...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051990(CHEMBL37446 | N-[3-(2,5-Dimethyl-pyrrolidin-1-yl)-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051980(2,2-Diphenyl-N-(3-piperidin-1-yl-propyl)-acetamide...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051982(CHEMBL288029 | N-(3-Morpholin-4-yl-propyl)-2,2-dip...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051977(2,2-Diphenyl-N-(2-piperidin-1-yl-ethyl)-acetamide ...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051981(2,2-Diphenyl-N-(4-piperidin-1-yl-butyl)-acetamide ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051987(CHEMBL37379 | N-(3-Dimethylamino-propyl)-2,2-diphe...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051983(CHEMBL40078 | N-[2-(1-Methyl-pyrrolidin-2-yl)-ethy...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051974(CHEMBL34069 | N-(3-Amino-propyl)-2,2-diphenyl-acet...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051989(CHEMBL435767 | N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-2,...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051970(CHEMBL285029 | N-(3-Dimethylamino-propyl)-N-methyl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051969(CHEMBL289225 | N-[3-(4-Methyl-piperazin-1-yl)-prop...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed