Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50006679
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052343BDBM50052343(3-Biphenyl-4-ylethynyl-1-aza-bicyclo[2.2.2]octan-3...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052350BDBM50052350(3-((E)-2-Biphenyl-4-yl-vinyl)-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052342BDBM50052342(3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052353BDBM50052353(3-(4-Benzothiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052355BDBM50052355(3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052377BDBM50052377(3-(Biphenyl-4-ylsulfanylmethyl)-1-aza-bicyclo[2.2....)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052376BDBM50052376(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octane | CHEMB...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052358BDBM50052358(3-(Biphenyl-4-yloxymethyl)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052351BDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052352BDBM50052352(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]oct-2-ene | CH...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052366BDBM50052366(3-(4'-Fluoro-biphenyl-4-yl)-1-aza-bicyclo[2.2.2]oc...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052367BDBM50052367(3-(Biphenyl-4-ylsulfanyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052357BDBM50052357(3-Biphenyl-4-ylmethyl-1-aza-bicyclo[2.2.2]octane |...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052341BDBM50052341(3-(4-Pyrimidin-2-yl-phenyl)-1-aza-bicyclo[2.2.2]oc...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052372BDBM50052372(3-(4-Thiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052364BDBM50052364(3-(4-Thiophen-2-yl-phenyl)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052373BDBM50052373(3-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylo...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052362BDBM50052362(3-(2-Phenyl-thiazol-5-yl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052344BDBM50052344(3-Biphenyl-3-yl-1-aza-bicyclo[2.2.2]octan-3-ol | C...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052361BDBM50052361(3-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylo...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052351BDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataIC50: 121nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052359BDBM50052359(3-(4'-Hydroxy-biphenyl-4-yl)-1-aza-bicyclo[2.2.2]o...)
Affinity DataIC50: 132nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052354BDBM50052354((1-Aza-bicyclo[2.2.2]oct-3-yl)-biphenyl-4-ylmethyl...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052345BDBM50052345(3-(4-Pyridin-4-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 161nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052356BDBM50052356(3-(4-Cyclohexyl-phenyl)-1-aza-bicyclo[2.2.2]octan-...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052360BDBM50052360(3-(4-Quinolin-3-yl-phenyl)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052378BDBM50052378(3-(4-Pyridin-2-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 240nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052374BDBM50052374(3-(4-Pyridin-3-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052349BDBM50052349(3-[1,1';4',1'']Terphenyl-4-yl-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50: 370nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052346BDBM50052346(3-((Z)-2-Biphenyl-4-yl-vinyl)-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50: 580nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052371BDBM50052371(Biphenyl-4-carboxylic acid (1-aza-bicyclo[2.2.2]oc...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052368BDBM50052368(3-[2,2']Bithiophenyl-5-yl-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052370BDBM50052370(3-(Biphenyl-4-sulfonyl)-1-aza-bicyclo[2.2.2]octane...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052340BDBM50052340(3-(4-[1,3]Dioxan-2-yl-phenyl)-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052365BDBM50052365(3-Biphenyl-4-yl-3-methoxy-1-aza-bicyclo[2.2.2]octa...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052363BDBM50052363(3-Phenyl-1-aza-bicyclo[2.2.2]octan-3-ol | CHEMBL10...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052369BDBM50052369((1-Aza-bicyclo[2.2.2]oct-3-yl)-biphenyl-4-yl-metha...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052348BDBM50052348(Biphenyl-4-sulfonic acid (1-aza-bicyclo[2.2.2]oct-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052369BDBM50052369((1-Aza-bicyclo[2.2.2]oct-3-yl)-biphenyl-4-yl-metha...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052375BDBM50052375(3-(Biphenyl-4-sulfonylmethyl)-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052347BDBM50052347(3-(Biphenyl-4-sulfinylmethyl)-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029160BDBM50029160(Disodium salt of 13-[-2,6,10-trimethyl-(6E,10E)-2,...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed