Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 50006696
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052464(1,8-Dihydroxy-10-(4-hydroxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052466(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052462(10-(2-Amino-phenylsulfanyl)-1,8-dihydroxy-10H-anth...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052457(1,8-Dihydroxy-10-(2-hydroxy-ethylsulfanyl)-10H-ant...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052470(1,8-Dihydroxy-10-(4-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  3.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052464(1,8-Dihydroxy-10-(4-hydroxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  3.00E+3nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052450(1,8-Dihydroxy-10-(2-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  3.00E+3nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052456(1,8-Dihydroxy-10-(2-hydroxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  5.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052450(1,8-Dihydroxy-10-(2-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  6.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052462(10-(2-Amino-phenylsulfanyl)-1,8-dihydroxy-10H-anth...)
Affinity DataIC50:  6.00E+3nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052459(10-(4-Amino-phenylsulfanyl)-1,8-dihydroxy-10H-anth...)
Affinity DataIC50:  7.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052460(1,8-Dihydroxy-10-phenylsulfanyl-10H-anthracen-9-on...)
Affinity DataIC50:  8.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052471(10-(2,3-Dihydroxy-propylsulfanyl)-1,8-dihydroxy-10...)
Affinity DataIC50:  9.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052469((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50:  1.30E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052473(1,8-Dihydroxy-10-(3-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  1.50E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052454(2-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  1.50E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052458(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  1.50E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052458(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  2.70E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052472(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052468(2-Amino-3-(4,5-dihydroxy-10-oxo-9,10-dihydro-anthr...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052459(10-(4-Amino-phenylsulfanyl)-1,8-dihydroxy-10H-anth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052461(1,8-Dihydroxy-10-(3-mercapto-propylsulfanyl)-10H-a...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052472(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052473(1,8-Dihydroxy-10-(3-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052474((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052461(1,8-Dihydroxy-10-(3-mercapto-propylsulfanyl)-10H-a...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052457(1,8-Dihydroxy-10-(2-hydroxy-ethylsulfanyl)-10H-ant...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052463(1,8-Dihydroxy-10-propylsulfanyl-10H-anthracen-9-on...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052455(1,8-Dihydroxy-10-phenethylsulfanyl-10H-anthracen-9...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052470(1,8-Dihydroxy-10-(4-methoxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052471(10-(2,3-Dihydroxy-propylsulfanyl)-1,8-dihydroxy-10...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052465(1,8-Dihydroxy-10-(4-methoxy-benzylsulfanyl)-10H-an...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052475((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052452(1,8-Dihydroxy-10-(3-phenyl-propylsulfanyl)-10H-ant...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052475((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052451(10-Ethylsulfanyl-1,8-dihydroxy-10H-anthracen-9-one...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052456(1,8-Dihydroxy-10-(2-hydroxy-phenylsulfanyl)-10H-an...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052469((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052453((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052467(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052466(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052467(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052468(2-Amino-3-(4,5-dihydroxy-10-oxo-9,10-dihydro-anthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052465(1,8-Dihydroxy-10-(4-methoxy-benzylsulfanyl)-10H-an...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052463(1,8-Dihydroxy-10-propylsulfanyl-10H-anthracen-9-on...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052460(1,8-Dihydroxy-10-phenylsulfanyl-10H-anthracen-9-on...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052452(1,8-Dihydroxy-10-(3-phenyl-propylsulfanyl)-10H-ant...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052455(1,8-Dihydroxy-10-phenethylsulfanyl-10H-anthracen-9...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052454(2-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052453((4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-yls...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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