Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50006708
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052612BDBM50052612(3-(5-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-...)
Affinity DataIC50: 380nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052602BDBM50052602(3-(4-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-...)
Affinity DataIC50: 450nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052596BDBM50052596(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052605BDBM50052605(3-(5-tert-Butyl-1,3-dioxo-1,3-dihydro-isoindol-2-y...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052608BDBM50052608(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052595BDBM50052595(3-(3,4-Diethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-i...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052611BDBM50052611(2-[1-(3,4-Dimethoxy-phenyl)-3-hydroxy-propyl]-isoi...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052613BDBM50052613(3-(4,7-Dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-y...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052606BDBM50052606(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052599BDBM50052599(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052600BDBM50052600(3-(5,6-Dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-y...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052619BDBM50052619(3-(3,4-Dimethoxy-phenyl)-3-(4-hydroxy-1,3-dioxo-1,...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052615BDBM50052615(3-(3,4-Dimethoxy-phenyl)-3-(5-nitro-1,3-dioxo-1,3-...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052617BDBM50052617(3-(3,5-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052609BDBM50052609(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-naphthal...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052610BDBM50052610(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052607BDBM50052607(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dip...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052618BDBM50052618(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052603BDBM50052603(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(4-metho...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052604BDBM50052604(3-(3,4-Dimethoxy-phenyl)-3-(4-nitro-1,3-dioxo-1,3-...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052616BDBM50052616(3-(3,4-Dichloro-phenyl)-3-(1,3-dioxo-1,3-dihydro-i...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052598BDBM50052598(N-Benzyl-3-(3,4-dimethoxy-phenyl)-3-(1,3-dioxo-1,3...)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052597BDBM50052597(3-(3-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoind...)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052601BDBM50052601(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-metho...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052614BDBM50052614(3-(4-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoind...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052620BDBM50052620(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-p...)
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed