Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50006708
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052612(3-(5-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052602(3-(4-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-...)
Affinity DataIC50:  450nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052596(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052605(3-(5-tert-Butyl-1,3-dioxo-1,3-dihydro-isoindol-2-y...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052608(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052595(3-(3,4-Diethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-i...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052611(2-[1-(3,4-Dimethoxy-phenyl)-3-hydroxy-propyl]-isoi...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052613(3-(4,7-Dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-y...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052599(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052606(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052600(3-(5,6-Dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-y...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052619(3-(3,4-Dimethoxy-phenyl)-3-(4-hydroxy-1,3-dioxo-1,...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052615(3-(3,4-Dimethoxy-phenyl)-3-(5-nitro-1,3-dioxo-1,3-...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052617(3-(3,5-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052609(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-naphthal...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052610(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052607(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dip...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052618(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052603(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(4-metho...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052604(3-(3,4-Dimethoxy-phenyl)-3-(4-nitro-1,3-dioxo-1,3-...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052616(3-(3,4-Dichloro-phenyl)-3-(1,3-dioxo-1,3-dihydro-i...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052598(CHEMBL109264 | N-Benzyl-3-(3,4-dimethoxy-phenyl)-3...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052597(3-(3-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoind...)
Affinity DataIC50:  8.90E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052601(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-metho...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052614(3-(4-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoind...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052620(3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-p...)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed