Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 324
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM566((3S,3aR,7aS)-hexahydro-2H-furo[2,3-b]pyran-3-yl N-...)
Affinity DataIC50:  1.20nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM563((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R...)
Affinity DataIC50:  1.80nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM573((3R,3aS,5R,6aS)-5-methyl-hexahydrofuro[2,3-b]furan...)
Affinity DataIC50:  4.10nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM565((3R,3aS,7aR)-hexahydro-2H-furo[2,3-b]pyran-3-yl N-...)
Affinity DataIC50:  4.20nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM564((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataIC50:  6.40nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM568((3S,4aS,8aS,2 R,3 S,3 aS,4 S,6 aR)-N-tert-Butyl-2-...)
Affinity DataIC50:  17nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM572((3R,3aS,6aR)-6a-methyl-hexahydrofuro[2,3-b]furan-3...)
Affinity DataIC50:  18.1nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM561((2S,3S)-2-(methoxymethyl)thiolan-3-yl N-[(2S,3R)-4...)
Affinity DataIC50:  19.7nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM562((2S,3S)-2-(methoxymethyl)-1,1-dioxo--thiolan-3-yl ...)
Affinity DataIC50:  23.8nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM574((3R,3aS,5S,6aS)-5-methyl-hexahydrofuro[2,3-b]furan...)
Affinity DataIC50:  27.1nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM567((3R,3aR,6aS)-hexahydro-2H-cyclopenta[b]furan-3-yl ...)
Affinity DataIC50:  190nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM569((3S,4aS,8aS,2 R,3 S)-N-tert-Butyl-2-[2 -hydroxy-4 ...)
Affinity DataIC50:  410nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM570((3R,3aR,6aR)-hexahydrofuro[2,3-c]furan-3-yl N-[(2S...)
Affinity DataIC50:  1.70E+3nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Illinois At Chicago

LigandPNGBDBM571((3R,3aS,6aR)-hexahydrofuro[3,2-b]furan-3-yl N-[(2S...)
Affinity DataIC50: >3.00E+3nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed