Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50006838
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataKi:  1.01nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  0.700nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054493(CHEMBL343805 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  0.710nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  1.10nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50:  1.12nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  1.36nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  1.52nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  6.20nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50:  14.2nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50:  16.6nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054493(CHEMBL343805 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  20.6nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054493(CHEMBL343805 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  74.5nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054503(CHEMBL263924 | N-((1S,2R)-3-Carbamimidoyl-2-hydrox...)
Affinity DataIC50:  111nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  125nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50:  137nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054495(CHEMBL422470 | Lactum Sulfonamide analogue)
Affinity DataIC50:  147nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(CHEMBL139656 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  157nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50:  159nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054495(CHEMBL422470 | Lactum Sulfonamide analogue)
Affinity DataIC50:  235nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054499(CHEMBL334454 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  286nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  290nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054499(CHEMBL334454 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  293nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054490(CHEMBL138243 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  420nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(CHEMBL139656 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  467nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50:  471nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50:  479nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  538nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  709nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50:  770nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  791nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054503(CHEMBL263924 | N-((1S,2R)-3-Carbamimidoyl-2-hydrox...)
Affinity DataIC50:  1.02E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054500(CHEMBL140646 | {(S)-1-[((S)-3-Carbamimidoyl-2-hydr...)
Affinity DataIC50:  1.46E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054495(CHEMBL422470 | Lactum Sulfonamide analogue)
Affinity DataIC50:  1.95E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054496((R)-N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054497(CHEMBL141043 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50: >2.50E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054490(CHEMBL138243 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054499(CHEMBL334454 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054496((R)-N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054490(CHEMBL138243 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054500(CHEMBL140646 | {(S)-1-[((S)-3-Carbamimidoyl-2-hydr...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  2.50E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054503(CHEMBL263924 | N-((1S,2R)-3-Carbamimidoyl-2-hydrox...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054497(CHEMBL141043 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(CHEMBL139656 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  2.50E+3nMAssay Description:compound was tested in vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054500(CHEMBL140646 | {(S)-1-[((S)-3-Carbamimidoyl-2-hydr...)
Affinity DataIC50:  1.68E+4nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed