Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50006838
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054498BDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: 0.700nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054493BDBM50054493(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 0.710nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054502BDBM50054502(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataKi:  1.01nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054492BDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50: 1.10nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054494BDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50: 1.12nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054492BDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50: 1.36nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054498BDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: 1.52nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054502BDBM50054502(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 6.20nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054504BDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50: 14.2nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054504BDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50: 16.6nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054493BDBM50054493(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 20.6nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054493BDBM50054493(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 74.5nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054503BDBM50054503(N-((1S,2R)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2...)
Affinity DataIC50: 111nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054505BDBM50054505(N-(3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S)-2-...)
Affinity DataIC50: 125nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054494BDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50: 137nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054495BDBM50054495(Lactum Sulfonamide analogue | CHEMBL422470)
Affinity DataIC50: 147nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054489BDBM50054489(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((R...)
Affinity DataIC50: 157nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054491BDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50: 159nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054495BDBM50054495(Lactum Sulfonamide analogue | CHEMBL422470)
Affinity DataIC50: 235nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054499BDBM50054499(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 286nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054492BDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50: 290nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054499BDBM50054499(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 293nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054490BDBM50054490(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-[(S...)
Affinity DataIC50: 420nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054489BDBM50054489(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((R...)
Affinity DataIC50: 467nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054494BDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50: 471nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054504BDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50: 479nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054505BDBM50054505(N-(3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S)-2-...)
Affinity DataIC50: 538nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054501BDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50: 709nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054491BDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50: 770nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054502BDBM50054502(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 791nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054503BDBM50054503(N-((1S,2R)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2...)
Affinity DataIC50: 1.02E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054491BDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054500BDBM50054500({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohexylc...)
Affinity DataIC50: 1.46E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054495BDBM50054495(Lactum Sulfonamide analogue | CHEMBL422470)
Affinity DataIC50: 1.95E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054489BDBM50054489(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((R...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054490BDBM50054490(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-[(S...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054496BDBM50054496((R)-N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054498BDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054501BDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50: 2.50E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054497BDBM50054497(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 2.50E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054503BDBM50054503(N-((1S,2R)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054500BDBM50054500({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohexylc...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054496BDBM50054496((R)-N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054502BDBM50054502(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054505BDBM50054505(N-(3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S)-2-...)
Affinity DataIC50: 2.50E+3nMAssay Description:compound was tested in vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054501BDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054490BDBM50054490(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-[(S...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054499BDBM50054499(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054497BDBM50054497(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054500BDBM50054500({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohexylc...)
Affinity DataIC50: 1.68E+4nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed