Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50006875
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054826BDBM50054826([7-([4,4']Bipiperidinyl-1-carbonyl)-3-oxo-4-phenet...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054827BDBM50054827({8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-o...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054830BDBM50054830([(R)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036089BDBM50036089([8-(4-Carbamimidoyl-phenylcarbamoyl)-3-oxo-4-phene...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036088BDBM50036088([(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054831BDBM50054831([7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3-oxo...)
Affinity DataKi:  4nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054824BDBM50054824({7-[Methyl-(3-piperidin-4-yl-propyl)-carbamoyl]-3-...)
Affinity DataKi:  8nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054829BDBM50054829([7-(3-Carbamimidoyl-phenylcarbamoyl)-3-oxo-4-phene...)
Affinity DataKi:  26nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054828BDBM50054828({7-[(3-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-o...)
Affinity DataKi:  90nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054825BDBM50054825([(S)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)